Quality control material and calibrator for calibrating blood cell analyzers and preparation method thereof

Abstract

A quality control material and a calibrator for calibrating blood cell analyzers comprise simian whole blood plasma, anticoagulant, preservation solution, cell mimics and stabilizer, wherein the weight ratio of the simian whole blood plasma to the anticoagulant is 10:1, the weight ratio of the mixture of the simian whole blood plasma and the anticoagulant to the preservation solution is 10:1, 1 percent by weight of stabilizer is added into the mixture of the three components, and the cell mimics are added according to the amount and concentration of products. The prices of the quality control material and the calibrator are reasonable, the quality of the quality control material and the calibrator is reliable, and the quality control material and the calibrator meet national sanitary requirement, and also can more accurately test the precision and stability of a blood cell analyzer.

Description

【Technical field】 [0001] The invention relates to a quality control product and a calibrator used for checking the accuracy and stability of a cell analyzer. 【Background technique】 [0002] The hematology analyzer is an indispensable screening device in daily inspections. It shoulders a large number of screening tasks for normal or abnormal specimens every day. Once an abnormality is found, the medical staff will immediately carry out the next step of relevant inspections to make judgments based on pathological data and related treatment or conditioning. Timely divert patients and healthy personnel, reduce medical workload and speed up medical work efficiency. [0003] Because blood cell analyzers analyze and report data on a large number of patients or normal physical examination samples every day, hospitals must determine whether the performance of the instrument meets the performance indicators at the factory every day, which requires specific reference materials. At pr...

AI Technical Summary

Problems solved by technology

[0004] Usually, the standard substances used in this instrument are sold by the instrument manufacturer, which gradually forms a monopoly. If the user does not use the matching reagents provided by the manufacturer but the domestically produced matching reagents, it is basically impossible for the user to buy their expensive standard substances. , while the prices of reagents supplied by manufacturers are often relatively high, resulting in the current high domestic medical costs

Furthermore, imported standard materials are often out of stock due to various restrictions, such as supply (manufacturers are also controlled), validity period (usually only three months, and less than two months to users), transportation method, and cycle time (Import basically takes more than a week), weather (must be stored at 2-8°C), etc. The reagents of the manufacturer of the instrument are not involved in the production of standard substances. They basically rely on several manufacturers in the United States for OEM production, so supporting It is particularly scarce and expensive in the hands of domestic users

[0005] There have been many manufacturers in China trying to develop and produce, but only two or three of them have used human blood to produce alternative standard substances, but the effect is still not good; especially in recent years, the state has banned human blood or its products from being sold as commodities, resulting in the Some manufacturers can only convert their raw materials into pig blood. Because pig blood is quite different from human blood cells, although the cost is low, the effect is far from that of human blood.