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Ointment and medicine composite formula for removing tinea unguium and preparation method thereof

A technology for onychomycosis and a medicament is applied in the field of medicament for removing onychomycosis, which can solve the problems of increasing the treatment cost of patients, unsustainable effect, unbalanced drug effect and the like, and achieves the effects of no toxic side effects, growth promotion and remarkable curative effect.

Inactive Publication Date: 2014-01-22
成美余
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The medicaments disclosed in the above two patents are not ideal for the treatment of onychomycosis. Some medicines have relatively large toxic and side effects, and are likely to cause adverse reactions such as skin allergies. The treatment process of some medicines is too long, and the efficacy is not balanced. , and the composition of the drug is too complicated and the cost is high, which increases the treatment cost of the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Combination preparations of ointments and medicaments for the removal of onychomycosis, including ointments for softening onychomycosis to facilitate the removal of onychomycosis and promoting the growth of new nails, and medicaments for killing fungus and promoting the growth of new nails For the growth of new nails, the composition and weight ratio of the ointment are as follows: 8% potassium iodide, 3% rostianil, 30% vaseline, 12% lanolin, 35% allantoin, and the balance is an additive. The additives described in this embodiment include zinc oxide and white wax, each accounting for half by weight.

[0026] In the present embodiment, the composition and weight ratio of the medicament are as follows: 15% of Radix chinensis, 15% of Sophora flavescens, 25% of hibiscus bark, 25% of impatiens, 5% of borneol, and the balance is 5% Acetic acid solution.

[0027] The preparation method of the ointment and medicament for removing onychomycosis comprises the following steps:

...

Embodiment 2

[0033] Ointment and medicament combination preparation for removing onychomycosis, comprise ointment and medicament, the composition and weight proportion of described ointment are as follows: potassium iodide 12%, rostianil 6%, vaseline 35%, lanolin 8% , Allantoin 25, the balance is an additive. The additives described in this embodiment include zinc oxide and white wax, each accounting for half by weight.

[0034] The composition and weight ratio of the medicament are as follows: 25% of Radix chinensis, 25% of Sophora flavescens, 15% of hibiscus bark, 15% of impatiens, 10% of borneol, and the balance is 10% acetic acid solution. The preparation method of described ointment and medicament is identical with embodiment one.

Embodiment 3

[0036] Ointment and medicament combination preparation for removing onychomycosis, including ointment and medicament, the composition and weight ratio of said ointment are as follows: 4% of dense tuozeng, 1% of light powder, 10% of potassium iodide, rostanil 5%, vaseline 30%, lanolin 10%, allantoin 30%, zinc oxide 5%, white wax 5%.

[0037] The composition and weight ratio of the medicament are: 20% of Radix radiata, 20% of Sophora flavescens, 20% of hibiscus bark, 20% of impatiens, 5% of borneol, and the balance is 6% acetic acid solution.

[0038] The preparation method of the ointment and medicament for removing onychomycosis comprises the following steps:

[0039] (1) Put the dense powder, light powder, potassium iodide, rottenil, vaseline, lanolin and white wax prepared in parts by weight into a container, mix and stir, and heat the container at the same time to melt the white wax;

[0040] (2) Add allantoin and zinc oxide prepared in parts by weight into the above mixtu...

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PUM

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Abstract

The invention relates to an ointment and medicine composite formula for removing tinea unguium and a preparation method thereof. The ointment comprises 3-5% of lithargyrum, 1-2% of calomel, 8-12% of potassium iodide, 3-6% of amorolfine, 25-35% of vaseline, 8-12% of lanolin, 25-35% of allantoin, and the balance of zinc oxide and white wax which account for 50% respectively. The medicine comprises 15-25% of radix stemonae, 15-25% of radix sophorae flavescentis, 15-25% of pseudolarix, 15-25% of balsam, 5-10% of borneol and the balance of vinegar. The preparation method comprises the following steps of: (1) mixing and stirring the accessories of the ointment, and heating to obtain ointment; and (2) grinding the accessories of the medicine into powder, and mixing the powder with the vinegar to obtain the medicine. The ointment is smeared to soften the nails with tinea unguium, and the medicine is applied to kill fungi and promote the growth of new nails. Through the invention, the cure rate is high, and the reoccurrence of tinea unguium can be effectively suppressed; and the ointment and medicine provided by the invention are safe without side effect and have an obvious curative effect and a short treatment period.

Description

technical field [0001] The invention relates to a medicament for removing onychomycosis, in particular to a combined preparation of ointment and medicament for removing onychomycosis and a preparation method thereof. Background technique [0002] Chinese patent CN1319563C discloses an external medicament for treating onychomycosis, which consists of three parts: A cream, B cream and liquid medicine. The effect of relieving itching, the invention is used in the process of treating onychomycosis, first use A ointment to remove diseased nails, then use liquid medicine to sterilize, and then use B ointment to promote the growth of new nails. [0003] Chinese patent CN101693040B discloses a medicament for treating onychomycosis and a preparation method thereof. The medicament includes an ointment for removing sick nails and a liquid medicine for killing fungi and promoting new nails. The composition and weight ratio of the ointment: 300-600 parts of urea, 100-200 parts of boric ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61K33/18A61K33/28A61K9/06A61P17/00A61P31/10A61K31/4166
Inventor 成美余
Owner 成美余
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