Application of dioscin in preparing medicament for preventing and treating diabetes mellitus

A technology for diabetes medicine and diosgenin is applied in the application field of diosgenin in the preparation of medicines for preventing and treating diabetes. The effect of increasing high-density lipoprotein levels
CN102552299AActive Publication Date: 2012-07-11DALIAN MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DALIAN MEDICAL UNIVERSITY
Publication Date
2012-07-11

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Abstract

The invention discloses application of dioscin in preparing a medicament for preventing and treating diabetes mellitus. According to the invention, the effects of dioscin in reducing blood-sugar content of various hyperglycemia models (I-type diabetes mellitus, II-type diabetes mellitus and acute hyperglycemia caused by adrenaline) and increasing the glycogen content of the hyperglycemia models are discovered, and the effects of the dioscin in improving the cell insulin resistance caused by high insulin, reducing contents of total cholesterol, triglyceride and low-density lipoprotein, increasing content of high-density lipoprotein and regulating fat metabolism disorder are simultaneously discovered, so that the application of the dioscin in preparing the medicament for preventing and treating the diabetes mellitus is invented. Various preparations prepared from the dioscin serving as a raw material according to pharmaceutically related requirement and clinical requirement can be applied clinically, and have the advantages of safety (no toxic or side effect), convenience, economy and the like.
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Description

technical field

[0001] The invention relates to a new application of diosgenin, in particular to the application of diosgenin in the preparation of drugs for preventing and treating diabetes. Background technique

[0002] At present, the incidence of diabetes is increasing at a rate of doubling every 15 years, and it has become the third largest disease after tumors and cardiovascular diseases. Because diabetes is accompanied by a series of complications, not only the patient feels great pain, but also brings a heavy burden to the family and the society. Therefore, finding a new drug for the prevention and treatment of diabetes with high efficiency and low toxicity is a hot research topic in the medical field. Since diabetes is divided into type Ⅰ diabetes and type Ⅱ diabetes, which are manifested as absolute insulin deficiency and insulin resistance, respectively, and type Ⅱ diabetes accounts for more than 90% of all diabetic patients, so improving insulin resistance is the...

Claims

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