Application of dencichine in preparation of medicament for treating neurodegenerative diseases

A technology of neurodegenerative diseases and panax notoginseng, which is applied in the field of medicine, can solve the problems of insignificant neurotoxicity and neurotoxicity of panax notoginseng
CN102579418AInactive Publication Date: 2012-07-18FOURTH MILITARY MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Publication Date
2012-07-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to application of a dencichine medicament, in particular to the application of a small dose of dencichine in preparation of a medicament for treating chronic neurologic diseases. A cytological method is used by researchers of the experiment, so that the condition that a small dose of dencichine can achieve a protection effect on neurogenic cell damages caused by a chronic anoxic effect is proved and a protection effect of a small dose of dencichine on the chronic neurologic diseases is prompted by a cellular morphology observation method, a cellular staining method and other methods by establishing a cellular chronic anoxic model and the like.
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Description

technical field

[0001] The invention relates to a new application of notoginseng, in particular to the application of notoginseng in the preparation of medicines for treating neurodegenerative diseases, and belongs to the field of medicine. Background technique

[0002] Neurodegenerative diseases refer to degenerative diseases of the nervous system caused by neuron degeneration and apoptosis. Histopathological studies have shown that neurons undergo slow and progressive apoptosis, and most of them have abnormal protein aggregation and inclusion bodies in neurons, suggesting that they may have similar pathogenesis, such as abnormal mitochondrial function due to genetic mutations, free radical production, excitatory Sexual toxicity, abnormal protein post-transcriptional modification, neurotrophic factor deficiency, etc., but the specific etiology is unknown. The clinical manifestations are mainly divided into two types: motor dysfunction and memory and cognitive dysfunction. ...

Claims

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