Application of dencichine in preparation of medicament for treating neurodegenerative diseases
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- FOURTH MILITARY MEDICAL UNIVERSITY
- Publication Date
- 2012-07-18
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to a new application of notoginseng, in particular to the application of notoginseng in the preparation of medicines for treating neurodegenerative diseases, and belongs to the field of medicine. Background technique
[0002] Neurodegenerative diseases refer to degenerative diseases of the nervous system caused by neuron degeneration and apoptosis. Histopathological studies have shown that neurons undergo slow and progressive apoptosis, and most of them have abnormal protein aggregation and inclusion bodies in neurons, suggesting that they may have similar pathogenesis, such as abnormal mitochondrial function due to genetic mutations, free radical production, excitatory Sexual toxicity, abnormal protein post-transcriptional modification, neurotrophic factor deficiency, etc., but the specific etiology is unknown. The clinical manifestations are mainly divided into two types: motor dysfunction and memory and cognitive dysfunction. ...