Medical disinfecting ultrasound gel composition and preparation method
A gel composition, ultrasonic technology, applied in echo/ultrasonic imaging agent, emulsion delivery, aerosol delivery and other directions, can solve the problems of unavoidable cross infection, easy rupture of condoms, etc., and achieve the effect of avoiding cross infection
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Embodiment 1
[0013] This example will illustrate an example of preparing 1000 g of the medical disinfectant ultrasonic gel composition of the present invention.
[0014] Product formula: 5 g carbomer, 0.5 g chitosan, 10 g glycerin, 3 g o-phthalaldehyde, 2 g m-phthalaldehyde, 1 g terephthalaldehyde, 1.0 g disodium EDTA, appropriate amount of NaOH, and the balance is deionized water.
[0015] Among them, carbomer-934 as a water-soluble polymer material accounts for 0.5% (i.e. 5g) of the total mass of the raw material reagent; chitosan as a bactericidal synergist component accounts for 0.05% (i.e. 0.5g) of the total mass of the raw material reagent ); Glycerin as an emollient and moisturizing component accounts for 1% (i.e. 10g) of the total mass of the raw material reagent; as a sterilizing component, o-phthalaldehyde, m-phthalaldehyde, and terephthalaldehyde mixture account for 1% of the total mass of the raw material reagent 0.6% (ie 6g); disodium EDTA as a stable component accounts for 0...
Embodiment 2
[0023] Product formula: carbomer 6 g, taurine 1 g, propylene glycol 20 g, o-phthalaldehyde 5 g, EDTA 0.5 g, appropriate amount of KOH, and the balance is deionized water.
[0024] Preparation method: Disperse carbomer in 94g deionized water, stir at 25°C (60-150 rpm) to disperse evenly, then change to slow stirring (60-120 rpm), add taurine respectively , propylene glycol, o-phthalaldehyde, more EDTA, make up the remaining amount of deionized water, add an appropriate amount of NaOH solution to adjust the viscosity, control the pH to 5.5-7.5, vacuum degassing for 5 minutes, and pack in a can.
Embodiment 3
[0026] Product formula: 8 g of carbomer, 1 g of chitosan, 30 g of glycerin, 6 g of isophthalaldehyde, 1 g of terephthalaldehyde, 2 g of disodium EDTA, an appropriate amount of citric acid, and the balance is deionized water.
[0027] Preparation method: Disperse carbomer in 90g deionized water, stir rapidly at 25°C to disperse evenly, then change to slow stirring, add chitosan, glycerin, isophthalaldehyde and terephthalaldehyde, disodium EDTA , make up the remaining amount of deionized water, add an appropriate amount of citric acid solution to adjust the viscosity, control the pH to 5.5-7.5, vacuum degassing for 10 minutes, and pack in cans.
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