Chinese medicinal composition for improving anoxia endurance and preparation method and application thereof

A composition and tolerance technology, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problems of high toxicity and side effects, inconvenient taking, etc., achieve strict compatibility, and enhance anti-stress ability , improve the effect of hypoxia resistance

Inactive Publication Date: 2012-08-01
窦媛媛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many drugs and supplements that are clinically used to improve hypoxia tolerance, but these varieties have relatively large toxic and side effects...

Method used

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  • Chinese medicinal composition for improving anoxia endurance and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: the preparation of granule

[0024] Take 30g of Rhodiola rosea, 40g of Daxueteng, 10g of bitter almond, 30g of Mutouhui and 10g of Jiulixiang medicinal materials, add water and decoct twice. Add water for the second time to 6 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.10 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 65%, stir, Let it stand for 24 hours, filter, reclaim ethanol from the filtrate and concentrate to the extract with a relative density of 1.10 (65°C), spray dry (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 80°C, and the material temperature is 70°C , the atomization pressure is 0.2 MPa, and the spray speed is 5ml / s.), crushed into dry extract powder, then add one or more auxiliary materials such as appropriate dextrin, soluble starch, mannitol, etc., w...

Embodiment 2

[0025] Embodiment 2: the preparation of tablet

[0026] Take 20g of Rhodiola rosea, 30g of Daxueteng, 5g of bitter almond, 20g of Mutouhui and 20g of Jiulixiang medicinal materials, add water to decoct twice, add water for the first time to 10 times the weight of medicinal materials, decoct for 2 hours, Add water once to 8 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.15 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 75%, stir, and statically Put it in place for 24 hours, filter, reclaim ethanol from the filtrate and concentrate it to an extract with a relative density of 1.25 (65°C), spray dry (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 90°C, and the material temperature is 80°C, The atomization pressure is 0.3 MPa, the spray speed is 7.5 / s.), crushed into dry extract powder, and th...

Embodiment 3

[0027] Embodiment 3: the preparation of oral liquid

[0028] Take 20g of Rhodiola rosea, 20g of Daxueteng, 5g of bitter almond, 20g of Mutouhui and 20g of Jiulixiang medicinal materials, add water and decoct twice, the first time add water 12 times the weight of the medicinal materials, decoct for 2 hours, Add water once to 10 times the weight of the medicinal materials, decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 85%, stir, and statically Put it in place for 24 hours, filter, reclaim ethanol from the filtrate and concentrate to the extract with a relative density of 1.30 (65°C), and spray dry (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 90°C, and the material temperature is 90°C, Atomization pressure is 0.4 MPa, and spray speed is 10 / s.), be ground into dry extract powder, c...

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Abstract

The invention discloses a Chinese medicinal composition for improving anoxia endurance. The Chinese medicinal composition contains 10-30 parts of rhodiola rosea, 20-40 parts of sargentg loryvine stem, 5-10 parts of bitter almond kernel, 10-30 parts of diversifolious patrinia root and 10-30 parts of murraya paniculata, and is in the dosage form of particle, tablet, oral liquid or capsule. The Chinese medicinal composition further discloses a preparation method of the Chinese medicinal composition. The method comprises the following steps of: adding water for decocting; concentrating; precipitating with alcohol; performing spray drying; smashing an obtained particle into dry extract powder; and adding auxiliary materials to obtain a needed preparation. The invention further discloses an application of the Chinese medicinal composition to preparation of a medicament for improving anoxia endurance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for improving hypoxia tolerance, a preparation method and application thereof. Background technique [0002] With the improvement of people's living standards, the demand for various health products that improve hypoxia tolerance is also increasing year by year. Health products that improve hypoxia tolerance play a very important role in improving people's quality of life. At present, there are a wide variety of health oral liquids for improving hypoxia tolerance on the market, and their functions and effects are also different. However, many health care products have the disadvantages of adding chemical drugs and taking them for a long time, which are harmful to the human body. There are many drugs and supplements that are clinically used to improve hypoxia tolerance, but these varieties have relativel...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P39/00
Inventor 不公告发明人
Owner 窦媛媛
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