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Composition comprising NO donor and dithiolane and its use for improvement of sexual function

一种组合物、性功能的技术,应用在份的摩尔量为基准为过量。领域,能够解决改善治疗方法等问题

Active Publication Date: 2014-08-06
INKRIPTA LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0024] In conclusion, there is currently no good treatment without serious side effects for improving sexual function or treating sexual dysfunction in both men and women

Method used

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  • Composition comprising NO donor and dithiolane and its use for improvement of sexual function
  • Composition comprising NO donor and dithiolane and its use for improvement of sexual function
  • Composition comprising NO donor and dithiolane and its use for improvement of sexual function

Examples

Experimental program
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Embodiment 1

[0083]

[0084] Packaged in polyethylene terephthalate bottles of 200ml and stored at 4°C.

Embodiment 2

[0086]

[0087] Packaged in polyethylene terephthalate bottles of 200ml and stored at 4°C.

Embodiment 3

[0089] alpha-lipoic acid

[0090] Packaged in polyethylene terephthalate bottles of 200ml and stored at 4°C.

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Abstract

The present invention relates to solid compositions comprising a substance which improves nitric oxide (NO) availability, re. an NO donor or a precursor of the biosynthesis of nitric oxide or an direct or indirect NO agonist, with arginine being a preferred compound, in combination with a dithiolane, with ±-lipoic acid as a preferred compound, and its use for improvement of sexual function. The compositions according to the invention comprise the NO donor or its precursor in excess, based on the molar amount of the constituents. The compositions are also suited for the improvement of sexual function. In particular the present invention relates to the use of a dithiolane in combination with a NO donor or a precursor thereof for the preparation of a medication for treatment of sexual dysfunction.

Description

[0001] This application is a patent application with the application number 200680028957.0 (PCT / EP2006 / 007733, international filing date August 4, 2006) that entered China on February 4, 2008, "combination of nitric oxide donor and dithiolane Substances and their use in improving sexual function". technical field [0002] The present invention relates to solid compositions comprising a substance improving the availability of nitric oxide, such as a nitric oxide donor or its biosynthetic nitric oxide precursor or a direct or indirect nitric oxide potentiator, Among them, arginine is the preferred compound, and combined with dithiolane, wherein the dithiolane is the preferred compound with α-lipoic acid, and this composition can be used to improve sexual function. According to the invention, the composition comprises a nitric oxide donor or a precursor thereof in excess based on the molar amount of the ingredients. This composition is also suitable for improving sexual function...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/385A61P15/08A61P15/10A61K31/198
CPCA61K31/385A61K31/198A61P15/00A61P15/08A61P15/10A61P15/12A61P43/00
Inventor 克劳斯·韦塞尔
Owner INKRIPTA LTD
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