Good-health traditional Chinese medicine preparation with improved stability

A technology of traditional Chinese medicine preparations and yams, which is applied in the direction of medical preparations containing active ingredients, pill delivery, sugar-coated pills, etc., and can solve problems such as short use time, large amount of auxiliary materials, and sticky preparations

Inactive Publication Date: 2012-09-19
聂有根
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the active ingredients of Ankang preparations are all water extracts of traditional Chinese medicines. The amount of extracts taken by Chinese medicine extracts is relatively large, and because they are water extracts, they have strong hygroscopicity. Absorbing moisture in the air will result in hygroscopic softening, sticky preparations, agglomeration and stickiness, which will seriously affect product quality after a long time. Therefore, how to overcome the above defects in the preparation of tablets and capsules is to reduce the use of excipients It is a technical problem that needs to be overcome when it is prepared into a preparation and can improve the stability of the preparation.
The current granules add a lot of excipients
However, the validity period of the current capsules and soft capsules is set at one and a half years. If the intermediate links of production and circulation are added, the actual use time of the preparation is very short, so its stability needs to be improved.

Method used

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  • Good-health traditional Chinese medicine preparation with improved stability
  • Good-health traditional Chinese medicine preparation with improved stability
  • Good-health traditional Chinese medicine preparation with improved stability

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] The preparation of embodiment 1 dry extract powder

[0057] The raw material medicine is composed of: 40g of red ginseng, 101.8g of white fungus, 101.8g of angelica, 101.8g of yam, 101.8g of pig spinal cord, 5.1g of antler, and 51g of hawthorn.

[0058] 1) Take deer antler, add 10 times the amount of water to cook for 3 hours, add red ginseng, angelica, yam, hawthorn, continue to add 7 times the amount of water to cook twice, the first time for 2 hours, the second time for 1 hour, combine Decoction, filtered.

[0059] 2) Take the porcine spinal cord, add 6 times the amount of water to decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction, and filter.

[0060] 3) Take white fungus and add 10 times the amount of water to decoct three times, the first time for 4 hours, the second and third times for 2 hours each, combine the decoction, and filter.

[0061] 4) The above three filtrates were combined, concentrated to a clear paste with...

Embodiment 2

[0063] Get the dry extract powder obtained by the method of Example 1, add starch according to the dry extract powder: starch weight ratio of 1: 1, mix well, make soft material, granulate, add an appropriate amount of magnesium stearate to the dried granule, mix Evenly, pressed into 1000 tablets, coated with film, to be ready.

[0064] Take the dry extract powder obtained by the method of Example 1, add starch according to the dry extract powder:starch weight ratio of 1:1, mix well, make soft material, granulate, and fill 1000 capsules with the dried granules.

Embodiment 3

[0066] Get the dry extract powder obtained by the method of Example 1, add a filler according to the dry extract powder: filler weight ratio of 1: 1, the filler is a mixture obtained by mixing starch and mannitol in a weight ratio of 2: 1, and make soft material, granulated, the dried granules are added with an appropriate amount of magnesium stearate, mixed evenly, compressed into 1000 tablets, film-coated, and obtained.

[0067] Get the dry extract powder obtained by the method of Example 1, add a filler according to the dry extract powder: filler weight ratio of 1: 1, the filler is a mixture obtained by mixing starch and mannitol in a weight ratio of 2: 1, and make soft material, granulated, and the dried granules are filled with 1000 capsules.

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly to a good-health traditional Chinese medicine preparation. The good-health traditional Chinese medicine preparation is characterized in that a spray drying process is selected for preparing dry extract powder, specific filling agents are combined, the hygroscopicity of tablets or capsules is improved, and the filling agents used by the good-health traditional Chinese medicine preparation are concretely the combination of starch and mannite or are only starch. The tablets or the capsules prepared from the good-health traditional Chinese medicine preparation have the advantages that the moisture absorption resistance performance is obviously improved, and the preparation stability is improved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an Ankang traditional Chinese medicine preparation with improved stability. Background technique [0002] The traditional Chinese medicine Ankang preparation is composed of 6 traditional Chinese medicines: red ginseng, white fungus, angelica, yam, pig spinal cord, deer antler, and hawthorn. It is used for dizziness, tinnitus, weakness of limbs, loss of appetite, lack of deep sleep, and dreaminess. Its prescription comes from the classic ancient Chinese medicine book "Synopsis of the Golden Chamber". [0003] In the prior art, Ankang Granules have been recorded in Volume 15 of the Ministry of Health's Pharmaceutical Standards for Traditional Chinese Medicine Prescriptions. The prescriptions are 44g red ginseng, 112g tremella, 112g angelica, 112g yam, 112g pig spinal cord, 5.6g velvet antler, and 56g hawthorn. The extract obtained from the raw ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/28A61K9/48A61P25/00A61K35/32A61K35/28
Inventor 聂有根
Owner 聂有根
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