Multi-mode little animal molecular image imaging device and imaging method

Abstract

A multimodal molecular image imaging device for a small animal and an imaging method therefor. The multimodal molecular image imaging device for a small animal comprises: an X-ray computed tomography (X-ray CT) system (3), a positron emission tomography (PET) system (2), a single photon emission computed tomography (SPECT) system (4), a fluorescence molecular tomography (FMT) system (1), a rotary rack system (5), a small animal bed system (6), a data acquisition system and a computer. Each imaging system is sampled by the data acquisition system through a data line for being stored in the computer. Each imaging system shares one small animal bed system (6) and one and the same examination shaft. The device acquires an X-ray CT / PET / SPECT / FMT tetramodal co-rack fused molecular medical image, can realize the complementation of advantages of different image equipment, and allows the image result acquired to be more precise and more reliable.

Description

technical field [0001] The invention relates to the field of biomedical imaging, in particular to a multimodal small animal molecular imaging device and imaging method. Background technique [0002] As the most advanced imaging technology in the field of biomedical engineering today, molecular medical imaging technology is the application of imaging methods to conduct qualitative and quantitative research on the biological processes in the living body at the cellular and molecular levels. Real-time, dynamic, in-vivo, non-invasive imaging technology for changes in the body. It is the key and core technology for researching targeted and specific molecular probes and therapeutic drugs. Multimodal molecular imaging technology can realize the complementary advantages of different imaging devices, making the obtained imaging results more accurate and reliable. Clinical practice has proved that multimodal molecular medical imaging equipment plays an important role in the early di...

AI Technical Summary

Problems solved by technology

[0005] PET / SPECT / CT three-modal imaging equipment has shortcomings such as insufficient specificity in function and difficulty in molecular target labeling. In addition, PET / SPECT is a nuclear medicine imaging method that uses the principle of positron annihilation for targeted imaging.

[0006] In the field of domestic small animal living imaging, there have been reports on small animal living imaging systems such as computed tomography CT, positron emission tomography PET, single photon emission tomography SPECT, and fluorescence tomography FMT. Multimodal imaging devices, for the field of molecular medical imaging, only PET and fluorescence imaging have practical application value, and X-ray CT and SPECT are not included

Moreover, each imaging system in the prior art only stays in concept, does not have practical significance, and cannot be used in actual work

At the same time, there is no direct correlation between the imaging systems of the four modalities, and they are not on the same inspection axis, so it is impossible to realize the fusion of multi-modal images on the same machine

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