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Composition containing glucose

A composition and technology of anhydrous glucose, applied in the field of medicine, can solve problems affecting drug dissolution, agglomeration, clump formation, etc.

Active Publication Date: 2014-09-10
西安安健药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, in the process of powder preparation and storage of finished products, various problems may be encountered, such as agglomeration and ball formation during the preparation process, which will affect drug packaging; agglomeration during storage may affect the dissolution of the drug during use

Method used

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  • Composition containing glucose
  • Composition containing glucose
  • Composition containing glucose

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] prescription: 1 part by weight of potassium chloride, 1.73 parts by weight of sodium chloride, 1.93 parts by weight of sodium citrate, and 9 parts by weight of glucose.

[0077] Preparation:

[0078] Four kinds of materials are crushed separately;

[0079] Mix the pulverized powders evenly;

[0080] Control the moisture content of the mixed powder, and if necessary, blow hot air or wet air to make the moisture content of the powder composition reach the range of 1.8-2.0%;

[0081] Packed into packaging bags to obtain the composition (which can be denoted as R1, and the composition of the present invention obtained hereinafter can be similarly represented).

Embodiment 2

[0083] prescription: 1 part by weight of potassium chloride, 2.33 parts by weight of sodium chloride, 1.93 parts by weight of sodium citrate, and 13.3 parts by weight of glucose.

[0084] Preparation: Referring to the method of Example 1, the moisture content of the composition reaches 1.7-1.9%, and the composition of the present invention (which can be recorded as R2) is obtained.

Embodiment 3

[0086] prescription: 1 part by weight of potassium chloride, 2.4 parts by weight of sodium chloride, 1.6 parts by weight of sodium citrate, and 14 parts by weight of glucose.

[0087] Preparation: Referring to the method of Example 1, the moisture content of the composition reaches 1.6-1.8%, and the composition of the present invention (which can be recorded as R3) is obtained.

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Abstract

The invention relates to a composition containing glucose. Specifically, the powder composition comprises glucose, halogen salt of potassium, halogen salt of sodium and the like. The composition has excellent medical performance.

Description

technical field [0001] The invention belongs to the technical field of medicines and relates to a powdery composition which contains glucose and salts of Na ions and K ions. Background technique [0002] Oral supplementation of salt in body fluids is the drug recommended by the World Health Organization for the treatment of acute diarrhea dehydration. These drugs have reasonable prescriptions, are cheap and easy to obtain, are convenient and efficient, and their speed of correcting dehydration is better than that of intravenous infusion. It is used to treat mild and moderate dehydration caused by indigestion and autumn diarrhea in children. [0003] It has been found that an effective formulation for salt replacement in body fluids contains dextrose, sodium chloride, potassium chloride, and sodium citrate as active ingredients, and the formulation can be directly Prepared into preparations, such as granules, powders and the like. In terms of the controllability of the phar...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/14A61K9/14A61P3/12A61P7/08A61K31/7004A61K31/194
Inventor 王伟
Owner 西安安健药业有限公司