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Emergency solution used for relieving burn of hydrofluoric acid

A technology of hydrofluoric acid and solution, which is applied in the direction of medical preparations containing active ingredients, active ingredients of aluminum/calcium/magnesium, drug delivery, etc., which can solve the problem of inevitable injury and so on, so as to relieve local pain and facilitate later treatment Effect

Inactive Publication Date: 2012-12-19
张家港市亚源高新技术材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] Due to the rapid penetration ability of fluoride ions to the subcutaneous tissue, time is of great significance for the on-site treatment of hydrofluoric acid poisoning. The traditional treatment method for poisoning caused by skin exposure is usually to wash with tap water for 15 to 30 minutes, and then apply gluconic acid. Calcium emulsion, and then handled by professional medical personnel, however, despite the above measures, serious injury is still inevitable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Dissolve 10g of borax in 88g of normal saline, add 5g of aluminum nitrate nonahydrate, stir and dissolve, the pH value of the solution measured at 10°C is 6.6, then add 0.1% benzalkonium chloride and 0.01% codeine of the total mass of the solution .

[0026] Take 50ml of the above solution, add 2ml of 40% hydrofluoric acid under the condition of electromagnetic stirring, after 1min, the concentrations of hydrogen ions and fluoride ions in the solution measured at 10°C are 3.2×10 -2 mol / L and 1×10 -4 mol / L, while adding 2ml of 40% hydrofluoric acid to an equal volume of pure water under the same conditions, the concentrations of hydrogen ions and fluoride ions were measured to be 0.92mol / L and 1×10 -2 mol / L, respectively 28.75 times and 100 times of the composition of the present invention.

Embodiment 2

[0028] 4% boric acid solution 80ml, 35ml 1.5mol / L sodium hydroxide, after mixing evenly, add 5.2g aluminum nitrate nonahydrate and 5g calcium gluconate, after stirring and dissolving, the pH value of the solution measured at 10°C is 6.6, then add 0.1% benzalkonium chloride and 0.01% codeine in the total mass of the solution.

[0029] Take 50ml of the above solution, add 2ml of 40% hydrofluoric acid under the condition of electromagnetic stirring, and after 1min, the concentrations of hydrogen ions and fluoride ions in the solution measured at 10°C are 4.0×10 -2 mol / L and 5.0×10 -4 mol / L, while adding 2ml of 40% hydrofluoric acid to an equal volume of pure water under the same conditions, the concentrations of hydrogen ions and fluoride ions were measured to be 0.92mol / L and 1×10 -2 mol / L, respectively 23 times and 20 times that of the composition of the present invention.

Embodiment 3

[0031] Mix 50ml of 1.0mol / L potassium dihydrogen phosphate and 55ml of 1.5mol / L sodium hydroxide, after mixing evenly, add 10g of aluminum nitrate nonahydrate, the pH value of the solution measured at 10°C is 6.5, and then add 0.1% of the total mass of the solution % Benzalkonium Chloride and 0.01% Codeine.

[0032] Take 50ml of the above solution, add 2ml of 40% hydrofluoric acid under the condition of electromagnetic stirring, after 1min, the concentrations of hydrogen ions and fluoride ions in the solution measured at 10°C are 3.2×10 -2 mol / L and 1×10 -5 mol / L, while adding 2ml of 40% hydrofluoric acid to an equal volume of pure water under the same conditions, the concentrations of hydrogen ions and fluoride ions were measured to be 0.92mol / L and 1×10 -2 mol / L, respectively 28.75 times and 1000 times of the composition of the present invention.

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Abstract

The invention provides an emergency solution used for relieving burn of hydrofluoric acid. A pH value of the emergency solution is 6-6.6; and the emergency solution comprises 2-5 wt% of a strong alkali and weak acid salt or an amino acid material used for neutralizing hydrogen ions, 4-10 wt% of a soluble aluminium salt used for complexing fluorine ions, 0.1-0.3 wt% of a material used for local anti-inflammation and 0.01-0.03 wt% of a material used for easing pain. The solution provided by the invention can effectively reduce poison and erosion effects on human body of the hydrogen ions and the fluorine ions; has the effects of relieving local pain and diminishing inflammation, can quickly treat injury accidents of hydrofluoric acid at a first scene of accidents, and is helpful for later treatment of traumas.

Description

technical field [0001] The invention relates to a solution for treating hydrofluoric acid burns, in particular to a composition capable of neutralizing hydrogen ions and fluoride ions and relieving local pain, which is used for rapid emergency on-site treatment of hydrofluoric acid burn accidents. Background technique [0002] Hydrofluoric acid is an important industrial raw material, which has important applications in semiconductor etching, glass etching, metal rust removal, petroleum refining, tanning, printing and dyeing, and the manufacture of various fluorine-containing fine chemicals. Hydrofluoric acid is also a highly toxic chemical substance, which can cause severe burns, poisoning and even death through contact with the skin, respiratory tract, mucous membranes, and gastrointestinal tract. Cases of hydrofluoric acid (or anhydrous hydrogen fluoride) poisoning appear in the newspapers from time to time. Although the traditional on-site emergency treatment methods of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K33/06A61K9/08A61P17/02
Inventor 杨瑞甫
Owner 张家港市亚源高新技术材料有限公司
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