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Extraction process of Ganoderma lucidum acidic components

An acidic component and extraction process technology, applied in the field of extraction process of Ganoderma lucidum acidic components, can solve the problems of large consumption of organic solvents, environmental pollution, low extraction selectivity, etc., and achieves economical cost and simple extraction and separation process operation. Effect

Inactive Publication Date: 2012-12-26
吴梦云
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Problems solved by technology

[0003] The traditional extraction method of Ganoderma lucidum triterpenoids is generally based on the difference in solubility. This method needs to consume a large amount of organic solvents, which is easy to cause environmental pollution, and the extraction selectivity is not high.

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] The invention adopts the ultrasonic-assisted alkaline method to extract the acidic components in the ganoderma lucidum. Taking the amount of obtained ganoderma acid substances and the content of ganoderma acid A as the examination indexes, the process was compared with the traditional extraction process.

[0017] The present invention mainly compares three kinds of extraction methods, which are chloroform-alcohol extraction method, ultrasonic-assisted alkaline extraction method and water-bath-assisted alkaline extraction method.

[0018] Ultrasonic-assisted alkaline extraction extracts triterpenoids from Ganoderma lucidum. Not only the types of target products extracted are the same as conventional methods, but also the target products can be extracted to the maximum. Among them, the amount of Ganoderma acid A is the object of investigation, compared with other extraction methods , especially showing the advantages of high extraction efficiency. At the same time, the p...

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Abstract

The invention relates to an extraction process of Ganoderma lucidum acidic components. The process employs an ultrasound-assisted alkaline method to extract acidic components in Ganoderma lucidum. According to the process, researches on different processes for separating and extracting Ganoderma lucidum acidic components are carried out, with amount of the obtained Ganoderma lucidum acidic substances and content of Ganoderma lucidum acid A as test indexes, so as to provide an ideal extraction process of Ganoderma lucidum acid A. Comparison on three extraction methods, including a chloroform-ethanol extraction method, an ultrasonic assisted alkali extraction method and a water bath auxiliary alkaline extraction method, is carried out.

Description

Technical field: [0001] The invention relates to an extraction process of the acidic components of the ganoderma lucidum, which uses an ultrasonic-assisted alkali method to extract the acidic components in the ganoderma lucidum. Background technique: [0002] Ganoderma lucidum is a fungus of the genus Ganoderma lucidum in the family Polyporaceae of Basidiomycetes. It has a long history of medicinal use in my country. Its acidic components (mainly triterpenoid ganoderma acid) have the functions of analgesia, sedation, inhibition of histamine release, detoxification, liver protection, and toxicity. It has functions such as killing tumor cells and is one of the main active ingredients of Ganoderma lucidum. Since Kutoba et al first isolated the triterpenoid ganoderma acids A and B from Ganoderma lucidum in 1982, the research on the separation, purification and pharmacological activity of ganoderma acids has always been an important content in the research of ganoderma. [0003] ...

Claims

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Application Information

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IPC IPC(8): A61K36/074A61P1/16A61P25/20A61P29/00A61P35/00A61P37/08
Inventor 吴梦云
Owner 吴梦云