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Application of traditional Chinese medicine composition in preparing drugs for treating secondary dysmenorrhea

A composition and secondary technology, applied in the direction of drug combination, disease, pharmaceutical formula, etc., can solve the problems of patients' price or side effects, difficult to adhere to, and pelvic ectopic lesions that are difficult to completely remove, etc.

Inactive Publication Date: 2013-01-09
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even the radical operation of hysterectomy still has the problem that pelvic heterotopic lesions are difficult to completely remove, and the postoperative recurrence rate is as high as 24.1%
In order to reduce recurrence, at present, Western medicine GnRH-a, danazol, etc. are often used as supplementary treatments after surgical resection of lesions, but many patients are difficult to adhere to because of the price or side effects

Method used

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  • Application of traditional Chinese medicine composition in preparing drugs for treating secondary dysmenorrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Angelica 30g, Motherwort 30g, Fried Puhuang 15g, Chuanxiong 10g, Wulingzhi 15g, Chishao 10g, Guizhi 10g, Atractylodes macrocephala 10g, Poria cocos 10g, peach kernel 10g, safflower 10g, adding water each time is 8% of the total weight of the medicinal materials. times, 6 times the volume, decocted twice in water, combined the filtrate, concentrated the water extract under reduced pressure to 200mL, divided into two bags, 100mL in each bag, 1 bag / time, 2 times / d, orally, 3-5d before menstruation Take 3-5 doses until the first day of menstrual cramps, and 3 menstrual cycles are a course of treatment.

Embodiment 2

[0068] Angelica 30g, Motherwort 30g, Fried Puhuang 15g, Chuanxiong 10g, Wulingzhi 15g, Chishao 10g, Guizhi 10g, Atractylodes macrocephala 10g, Poria cocos 10g, peach kernel 10g, safflower 10g, adding water each time is 8% of the total weight of the medicinal materials. times, 6 times the volume, decocted in water for 2 times, combined the filtrate, concentrated the water extract under reduced pressure, mixed, sieved, then mixed with 300g of starch, and prepared with starch slurry (take 220g of starch to make starch slurry with water) Granules, sieved, dried and capsuled.

Embodiment 3

[0070] Angelica 30g, Motherwort 30g, Fried Puhuang 15g, Chuanxiong 10g, Wulingzhi 15g, Chishao 10g, Guizhi 10g, Atractylodes macrocephala 10g, Poria cocos 10g, peach kernel 10g, safflower 10g, adding water each time is 8% of the total weight of the medicinal materials. times, 6 times the volume, decocted twice in water, combined the filtrate, concentrated the water extract under reduced pressure to 35ml, added distilled water, stirred to dissolve, appropriate amount of sucrose, added distilled water to 1000ml, stirred evenly, filtered, and put the filtrate in sterile Filling under conditions, each 5ml sealed to obtain oral liquid.

[0071]

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparing drugs for treating secondary dysmenorrhea. The traditional Chinese medicine composition comprises 30g of Chinese angelica, 30g of motherwort herbs, 15g of fried cattail pollen, 10g of Sichuan lovage rhizome, 15g of flying squirrels droppings, 10g of red peony roots, 10g of cassia twigs, 10g of largehead atractylodes rhizome, 10g of Indian bread, 10g of peach kernels and 10g of red flowers, water is added into the mixture with the volume of 8 times of total weight of medical materials and 6 times of total weight of the medical materials respectively every time, the mixture is decocted and boiled for two times in the water, then filter liquids are combined, and the decompressed concentrated water is extracted. According to the application of the traditional Chinese medicine composition in preparing the drugs for treating the secondary dysmenorrheal, on the basis of differentiation and treatment theories of traditional Chinese medical science, the traditional Chinese medicine composition is formed by combining a plurality of years of clinical experience; on the basis that three parts of analgesia prescriptions before menstruation are used to treat primary dysmenorrheal, the peach kernels and the red flowers are added and have obvious curative effects in treating the secondary dysmenorrheal caused by endometriosis, adenomyosis, pelvic inflammation and the like, and particularly, the curative effect in treating the secondary dysmenorrheal caused by the endometriosis reaches 96.4%.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to the application of a traditional Chinese medicine composition in preparing a medicine for treating secondary dysmenorrhea. Background technique [0002] Endometriosis (EMS), referred to as endometriosis, refers to the appearance, growth, invasion, and periodic bleeding of the endometrium outside the uterine cavity, causing pain, infertility, and nodular masses. Its incidence rate is as high as 10-15% in women of childbearing age, and has a clear upward trend, becoming a frequently-occurring and difficult disease. 80% of EMS patients have obvious dysmenorrhea and pelvic pain, and 50% are infertile, seriously affecting women's health and quality of life. Western medicine treatment methods for EMS are mainly divided into drug therapy and surgical treatment. Drug therapy is mainly to inhibit the secretion of estrogen and create a low estrogen environment to achiev...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P15/00A61K35/24
Inventor 方玲
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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