Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Traditional Chinese medicine extract of total saponin ingredients and preparation method of same

A technology of extracts and total saponins, which is applied in the field of traditional Chinese medicine extracts of total saponins and its preparation, can solve the problems of few applications, and achieve the effects of low cost, improvement of symptoms, and convenient preparation methods

Inactive Publication Date: 2013-01-16
BAOTOU CHINESE TRADITIONAL MEDICINE
View PDF0 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Macroporous separation technology is widely used in domestic extract production enterprises, but rarely used in the production of Chinese patent medicines

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Respectively remove impurities from Lily and Anemarrhena, wash, and dry at a low temperature of 50-60°C;

[0023] (2) After mixing Lily and Anemarrhena, soak overnight at 50°C with 2 times the amount of 70% ethanol, and start percolation. Add 3 times of water for diafiltration, and collect the aqueous solution as B.

[0024] (3) Recover ethanol from A to obtain a concentrated liquid C with a weight of 1:1 medicinal material, and mix B and C.

[0025] (4) Filtration (ceramic membrane) or microfiltration.

[0026] (5) Adsorb on the PlPl01 resin column at a speed of 2ml / min.

[0027] (6) Wash with 10 times the column volume of purified water, backwash with 4 times the column volume of 70% ethanol, recover the 70% ethanol solution, concentrate, and dry.

[0028] (7) The dry matter is crushed and passed through a 100-mesh sieve.

Embodiment 2

[0030] (1) Remove impurities from Lily and Anemarrhena, wash and dry at 60-70°C;

[0031] (2) After mixing Lily and Anemarrhena, soak overnight at 50°C with 4 times the amount of 70% ethanol, and start percolation. Add 5 times of water for diafiltration, and collect the aqueous solution as B.

[0032] (3) Recover ethanol from A to obtain a concentrated liquid C with a weight of 1:1 medicinal material, and mix B and C.

[0033] (4) Filtration (ceramic membrane) or microfiltration.

[0034] (5) Adsorb on the PlPl01 resin column at a speed of 3ml / min.

[0035] (6) Wash with purified water for 8 times the column volume, backwash with 70% ethanol for 5 times the column volume, recover the 70% ethanol solution, concentrate, and dry.

[0036] (7) The dry matter is crushed and passed through a 100-mesh sieve.

Embodiment 3

[0038] (1) Respectively remove impurities from Lily and Anemarrhena, wash, and dry at a low temperature of 50-70°C;

[0039] (2) After mixing Lily and Anemarrhena, soak overnight at 50°C with 3 times the amount of 70% ethanol, and start percolation. Add 3 times of water for diafiltration, and collect the aqueous solution as B.

[0040] (3) Recover ethanol from A to obtain a concentrated liquid C with a weight of 1:1 medicinal material, and mix B and C.

[0041] (4) Filtration (ceramic membrane) or microfiltration.

[0042] (5) Adsorb on the PlPl01 resin column at a speed of 2ml / min.

[0043] (6) Wash with 10 times the column volume of purified water, backwash with 5 times the column volume of 70% ethanol, recover the 70% ethanol solution, concentrate, and dry.

[0044] (7) The dry matter is crushed and passed through an 80-mesh sieve.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine (TCM) extract of total saponin ingredients and a preparation method of same. Raw materials for extracting the extract are 10-90 percent of lily and 10-90 percent of rhizoma anemarrhenae. All components are produced by adopting the following steps: purifying lily and rhizoma anemarrhenae, cleaning and then drying at low temperature of 50-70 DEG C; soaking lily and rhizoma anemarrhenae in alcohol, infiltering the alcohol and collecting alcohol liquor as A; adding water in residue for infiltration and collecting water solution as B; reclaiming A to alcohol to obtain a concentrated solution C with the herb weight of 1:1, and mixing B and C; filtering (a ceramic membrane) or micro-filtering; loading a P1P101 resin column at the speed of 2-3 ml / min for adsorption; and washing, backwashing with alcohol, concentrating, drying, crushing and screening. The invention has the advantages that as the extract contains saponin, a research shows that the extract can play a role of improving the symptom of a chronic stress induced depression model rat and can be used for curing human depression; and the preparation method is convenient, the cost is low, the implementation is easy, deficiencies in the prior art are made up, and a broad way is provided for development of the medicine industry.

Description

1. Technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine extract of total saponins and a preparation method thereof. 2. Technical background [0002] Chinese medicine extract is a new type of traditional Chinese medicine product of modern pharmaceutical technology, and has a broad market space. The extract is the carrier of modern herbal medicine and a new product form in the international natural medicine and health care products market. This kind of product is produced under the requirements of GAP and GMP, and adopts advanced technology and testing technology at the same time. Macropore separation technology is widely used in domestic extract production enterprises, but it is rarely used in the production of Chinese patent medicines. 3. Contents of the invention [0003] The object of the present invention is to provide a kind of Chinese medicine extract and its preparati...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8967A61P25/24
Inventor 李卫民贾金良杨丽
Owner BAOTOU CHINESE TRADITIONAL MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com