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Chinese medicinal preparation for preventing and treating depression

A technology of traditional Chinese medicine preparations and depression, which is applied in the field of traditional Chinese medicine preparations for the prevention and treatment of depression, and can solve the problems that the treatment effect needs to be strengthened and improved

Active Publication Date: 2014-03-26
广州市精神病医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the application of treatment, it is found that the therapeutic effect of this prescription still needs to be strengthened and improved.

Method used

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  • Chinese medicinal preparation for preventing and treating depression
  • Chinese medicinal preparation for preventing and treating depression
  • Chinese medicinal preparation for preventing and treating depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The Chinese medicine preparation for preventing and treating depression described in the present embodiment: its active ingredient is prepared from the following raw materials: Bupleurum bupleuri 12g, Radix Paeoniae Alba 12g, Angelica 12g, Atractylodes macrocephala 10g, Poria cocos 12g, Curcuma 10g, Cortex Albizia 12g , Polygala 8g, Suanzaoren 12g, Rhizoma Cyperi 8g, Oyster 30g, Zhigancao 6g.

[0014] The preparation method of the traditional Chinese medicine preparation for preventing and treating depression is as follows: first add 8 times the amount of water to the above medicinal materials, soak for 30 minutes, decoct for 1 hour, decoct twice, filter the juice and discard the residue, combine the medicinal liquid, concentrate to 400ml, Containing crude drug amount 185g. Concentrate the medicinal solution to 37g / ml and refrigerate for later use.

Embodiment 2

[0016] 1. Materials

[0017] 1.1 Animals 48 clean-grade healthy female Wistar rats, aged 6-8 weeks, weighing (200±20) g, were provided by the Experimental Animal Center of Southern Medical University (scxk Guangdong 2006-0015). According to body weight, they were randomly divided into normal group, model group, high-dose Xiaoyao powder group, middle-dose Xiaoyao powder group, low-dose Xiaoyao powder group, and sertraline group, with 8 rats in each group.

[0018] 1.2 Drug control group (original prescription): Bupleurum 10g, Baishao 12g, Angelica 6g, Atractylodes macrocephala 10g, Poria cocos 15g, Curcuma 10g, Albizia juniper 15g, Polygala 6g, Suanzaoren 15g, Rhizoma Cyperi 10g, Licorice 6g. Decoct in water twice, filter the juice and discard the dregs, combine the medicinal liquid, and decoct a total of 400ml medicinal liquid, containing 115g of crude drug. Concentrate the medicinal solution to 23g / ml and refrigerate for later use.

[0019] The traditional Chinese medicine ...

Embodiment 3

[0060] Embodiment 3 clinical data

[0061] 1.1 General data Observation cases 80 cases were patients with depression in Guangzhou Brain Hospital. They were randomly divided into a treatment group (current prescription) and a control group (original prescription), 40 cases in each group. In the treatment group, there were 16 males and 24 females; the age was 25-54 years old, with an average of 38 years old; the course of disease was 1-8 years, with an average of 5.6 years. In the control group, there were 18 males and 22 females; their age ranged from 23 to 51 years, with an average of 37.3 years; the course of disease ranged from 1.5 to 7 years, with an average of 5.5 years. There was no significant difference in age, gender, and disease course between the two groups (P>0.05), which were comparable.

[0062] 1.2 Diagnostic criteria

[0063] 1.2.1 Western medicine diagnostic criteria All cases meet the diagnostic criteria for depression in the "Chinese Classification and Diagn...

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Abstract

The invention discloses a Chinese medicinal preparation for preventing and treating depression. Active ingredients of the Chinese medicinal preparation are prepared from the following bulk pharmaceuticals in parts by weight: 11.5-12.5 parts of Chinese thorowax root, 11.5-12.5 parts of white paeony root, 11.8-12.3 parts of Chinese angelica, 9.5-11.5 parts of large-head atractylodes rhizome, 11.5-12.5 parts of indian buead, 11.8-12.3 parts of turmeric root-tuber, 11.5-12.5 parts of silktree albizzia bark, 7.8-8.3 parts of thinleaf milkwort root-bark, 11.5-12.5 parts of spina date seed, 7.8-8.3 parts of nutgrass galingale rhizome, 29-31 parts of oyster and 5.8-6.2 parts of roasted liquoric root. The Chinese medicinal preparation for preventing and treating depression has a very good curative effect, can be used for smoothing liver, resolving depression, regulating blood, invigorating spleen, supplementing qi and smoothing nerves. The Chinese medicinal preparation can be mainly used for treating mild or moderate depression due to liver depression and spleen deficiency.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for preventing and treating depression. Background technique [0002] Depression is a group of mood disorders (mood disorders) with depression as the main symptom caused by various reasons. The clinical manifestations are depressed mood, slow thinking, decreased speech and action, and low self-evaluation, accompanied by physical symptoms such as loss of appetite, sexual dysfunction, and sleep disturbance. Clinically, it is chronic and recurrent. With the acceleration of the pace of life and the intensification of social competition, people's mental pressure is gradually increasing, and depression has become a common disease with a high incidence in modern society. Epidemiological studies have shown that in 1994 the World Health Organization (WHO) surveyed 15 grassroots units in the world, and the results showed t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P25/24
Inventor 丁国安于林朱志敏黄俊东伍远菲葛鑫宇
Owner 广州市精神病医院
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