Drug composite for treating sensitive skin and preparation method thereof

A composition and sensitivity technology, which is applied in the direction of drug combination, skin care preparations, skin diseases, etc., can solve the problems of lack of effective means to treat sensitive skin, and achieve the effect of no side effects, good safety and clear effect

Active Publication Date: 2013-03-20
GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The concept of sensitive skin has only been put forward for more than 20 years, and people still lack effective means to treat sensitive skin

Method used

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  • Drug composite for treating sensitive skin and preparation method thereof
  • Drug composite for treating sensitive skin and preparation method thereof
  • Drug composite for treating sensitive skin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] At room temperature, take 10 kilograms each of Sophora flavescens, Nepeta nepeta, Qingtiankui, Houttuynia cordata and honeysuckle (50 kilograms in total), soak and extract with 600 kilograms of ethanol with a volume concentration of 70%, the soaking time is 24 hours, and the residue is reused 600 kg of ethanol with a concentration of 70% was soaked for 24 hours to extract, then the soaked solutions were combined, filtered through a 200-mesh filter, concentrated 20 times under reduced pressure, and then the concentrated solution was placed on a macroporous resin, and the concentrated solution was mixed with ethanol with a volume concentration of 50%. Elution, the collected eluate contains the active ingredients required in the prescription of the present invention, that is, the pharmaceutical composition.

Embodiment 2

[0040] At room temperature, take 8 kilograms of Sophora flavescens, 8 kilograms of Nepeta, 12 kilograms of Heliotrope, 12 kilograms of Houttuynia cordata and 12 kilograms of honeysuckle (52 kilograms in total), soak and extract with 1200 kilograms of ethanol with a volume concentration of 50%, and the soaking time is After 24 hours, the residue was soaked in 1200 kg of ethanol with a volume concentration of 50% for 24 hours to extract, then the soaked solutions were combined, filtered through a 200-mesh filter, concentrated under reduced pressure for 40 times, and then the concentrated solution was covered with macroporous resin. It is eluted with ethanol with a volume concentration of 40%, and the collected eluate contains the active ingredient required in the prescription of the present invention, that is, the pharmaceutical composition.

Embodiment 3

[0042] At room temperature, take 8 kilograms of Sophora flavescens, 8 kilograms of Nepeta, 15 kilograms of Qingtiankuai, 15 kilograms of Houttuynia cordata and 15 kilograms of honeysuckle (61 kilograms in total), soak and extract with 1000 kilograms of ethanol with a volume concentration of 80%, and the soaking time is After 24 hours, the residue was soaked in 1000 kg of ethanol with a volume concentration of 80% for 24 hours to extract, then the soaked solutions were combined, filtered through a 200-mesh filter, and concentrated 25 times, and then the concentrated solution was covered with a macroporous resin, and the volume concentration 60% ethanol is used for elution, and the collected eluate contains the active ingredient required in the prescription of the present invention, that is, the pharmaceutical composition.

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Abstract

The invention provides a drug composite for treating sensitive skin and a preparation method thereof. The drug composite with an effect on treating sensitive skin is prepared from the following raw materials in parts by weight: 1-60 parts of radix sophorae flavescentis, 1-60 parts of herba schizonepetae, 1-60 parts of nervilia fordii schltr, 1-60 parts of houttuynia cordata and 1-60 parts of honeysuckle flowers. The drug composite provided by the invention has the advantages of obvious effect and safety on treating sensitive skin without stimulation or sensitization on skin.

Description

technical field [0001] The present invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for cosmetics with the effect of treating sensitive skin, a preparation method and application thereof, suitable for being added to ointments, creams, milks and liquids Cosmetics (except perfume). Background technique [0002] Sensitive skin is ubiquitous as a common troublesome skin condition. Although the exact definition of sensitive skin has not yet been agreed, the description of clinical symptoms and signs of its skin is gradually consistent, that is, discomfort, which is almost always manifested in the face of most patients, including Subjective sensory symptoms such as burning, stinging, itching, tingling, which may or may not be accompanied by erythema. (ProkschE, Weidinger S. New insights into the pathogenesis of sensitive skin. Hautarzt, 2011, 62(12): 900-5) Although sensitive skin is not a skin disea...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K8/97A61P17/00A61Q19/00A61Q19/10
Inventor 王恩瀚
Owner GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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