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Method for eliminating interference side lobe signal, system thereof and blood cell analyzer

A technology to eliminate interference and side lobes, applied in the field of medical signal processing, can solve problems such as rising costs and high requirements for optical component parameters

Active Publication Date: 2013-05-08
SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the embodiment of the present invention is to provide a method for eliminating the interference side lobe signal, aiming at solving the requirement of eliminating the interference side lobe signal by improving the performance of the optical element parameters in the prior art. Due to the high requirements for the parameters of the optical element, the cost is greatly increased. rising issue

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  • Method for eliminating interference side lobe signal, system thereof and blood cell analyzer
  • Method for eliminating interference side lobe signal, system thereof and blood cell analyzer
  • Method for eliminating interference side lobe signal, system thereof and blood cell analyzer

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Embodiment 1

[0038] The application scenario of this embodiment can be: when the blood cell analyzer using the optical method recognizes and measures cells, such as platelet cells, the scattered light signal generated by the cells after laser irradiation is photoelectrically converted by the sensor, and the optical signal is converted into an electrical analog Signal, the converted electrical analog signal is subjected to signal shaping, for example, amplification, filtering, or clipping, etc., so that the frequency and amplitude of the electrical signal are limited within a certain range, and the electrical analog signal after signal shaping is digitally quantized , to obtain the corresponding digital signal, by processing the digital signal, to remove the influence of the side lobe on the measured cells, for example, the side lobe signal of the red blood cell or white blood cell is the interference side lobe of the platelet cell, and the following examples are specifically described , fi...

Embodiment 2

[0054] figure 2 A flow chart showing the implementation of the method for eliminating interference sidelobe signals provided by Embodiment 2 of the present invention is described in detail as follows:

[0055] In step S201, the scattered light signal of cells irradiated by laser is received, the scattered light signal is converted into a digital signal, and the signal feature information in the digital signal is obtained, the signal feature information is pulse peak value, pulse peak time and impulse baseline.

[0056] In step S202, the pulse baseline included in the pulse peak value is removed to obtain the pulse relative peak value.

[0057] In this embodiment, step S202 may be specifically subtracting the pulse baseline from the pulse peak value to obtain the pulse relative peak value, wherein the pulse baseline may be subtracted from the pulse peak value through signal processing, or The pulse baseline contained in the pulse peak value may be removed through a hardware ...

Embodiment 3

[0075] Figure 6 It is a system structure diagram of the application scene of this embodiment: when the blood cell analyzer adopts the optical method to measure cells, such as platelet cells, the scattered light signal generated by the cells after laser irradiation is photoelectrically converted by the sensor 61, and the optical signal Convert the converted electrical analog signal to a signal conditioning circuit 62 for signal shaping, such as amplification, filtering, or clipping, so that the frequency and amplitude of the electrical signal are limited within a certain range, and the signal is shaped The final electrical analog signal is digitally quantized by the analog-to-digital conversion circuit 63 to obtain a corresponding digital signal. The digital signal enters the system 64 for eliminating interference side lobe signals. Level side lobes or multi-level side lobes, for example, the side lobe signal of red blood cells or white blood cells is the interference side lob...

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Abstract

The invention is suitable for the technical field of medical signal processing, and provides a method for eliminating an interference side lobe signal, a system thereof and a blood cell analyzer. The method comprises the following steps: receiving a diffusion light signal obtained through irradiating a cell by laser, converting the diffusion light signal into a digital signal, and acquiring the signal characteristic information in the digital signal; searching the interference side lobe signal in the digital signal according to the signal characteristic information; and rejecting the interference side lobe signal in the digital signal. The interference side lobe signal is eliminated without improving optical element parameters when an optical diffusion process is used to identify cells, such as a platelet cell, so requirements on the optical element parameters are reduced, thereby the material cost is reduced, and the accuracy of the cell identification using the optical diffusion process is improved.

Description

technical field [0001] The invention belongs to the technical field of medical signal processing, and in particular relates to a method, a system and a blood cell analyzer for eliminating interference side lobe signals. Background technique [0002] There are two main methods for blood cell detection by blood cell analyzers: one is the impedance method, and the other is the optical method. Most of the early blood analyzers used the impedance method to measure blood cells. The specific principle of the impedance method is the Coulter principle, which uses the change of impedance at both ends of the small hole when the blood cells flow through the small hole for detection. With the advancement of cell detection technology, the optical method came into being. The specific principle is to irradiate the blood cells flowing through the irradiation area with laser light of a specific wavelength, and collect the scattered light of blood cells at multiple angles or combine with fluor...

Claims

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Application Information

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IPC IPC(8): G01N21/01G01N21/47
Inventor 郁琦代勇
Owner SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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