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Tooth-cleaning antimicrobial gel recipe and preparation method thereof
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A technology of gel and tooth cleaning, which is applied in the field of tooth cleaning antibacterial gel and dressings containing chitosan iodine
Active Publication Date: 2014-11-26
GUIZHOU YANGSHENG MEDICAL INSTR
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Abstract
Description
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In the Chinese patent database, there are dozens of patent applications related to tooth cleaning, such as No. 200480008206.3 "Hydrogel Composition for Teeth Whitening", No. 200610035086.7 "An Elastic Gel Deep Whitening Teeth Sticker" , No. 200910115132.8 "Gel for Teeth Bleaching and Whitening", No. 201110413207.8 "Powerful Teeth Bleaching Gel for Dental Clinics", etc., but so far, there is no patent application for using chitosan iodine to make antibacterial gel preparations for tooth cleaning
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Embodiment l
[0038] Example 1 Weighing ingredients according to the following raw material quality formula: chitosan iodine 0.25g, glacial acetic acid 0.125g, polysorbate-20 0.75g, glycerol 2.5g, potassium iodate 0.025g, sorbitol 30g, silicon dioxide 12g, Cocamidopropyl betaine 8g, peppermint essence 0.5g, purified water added to 100g. Add glacial acetic acid, polysorbate-20, glycerol, and part of purified water to chitosan iodine and stir well to dissolve completely, and set aside; then take a small amount of purified water to dissolve potassium iodate, and add it to the spare material to mix , stir evenly; then continue to add sorbitol, silicon dioxide, cocamidopropyl betaine, and peppermint essence to the mixture according to the quality formula of the raw materials, add the remaining purified water to 100g, stir slowly to form a gel, and obtain The finished product of tooth cleaning and antibacterial gel.
Embodiment 2
[0039] Example 2 Weighing ingredients according to the following raw material quality formula: chitosan iodine 0.6g, glacial acetic acid 0.3g, polysorbate-20 1.8g, glycerol 6.0g, potassium iodate 0.1g, sorbitol 36g, silicon dioxide 13g, Cocamidopropyl betaine 12g, peppermint essence 1.0g, purified water added to 100g. The preparation method is the same as that of Example 1, and the finished product of tooth cleaning and antibacterial gel is obtained.
Embodiment 3
[0040] Example 3 Weigh ingredients according to the following raw material quality formula: chitosan iodine 2g, glacial acetic acid 1g, polysorbate-20 3g, glycerol 7g, potassium iodate 0.2g, sorbitol 40g, silicon dioxide 18g, cocamide propane Base betaine 13g, peppermint essence 1.5g, purified water added to 100g. The preparation method is the same as that of Example 1, and the finished product of tooth cleaning and antibacterial gel is obtained.
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Abstract
The invention discloses a tooth-cleaning antimicrobial gel recipe and a preparation method thereof. The gel comprises raw materials of chitosan-iodine, glacial acetic acid, polysorbate-20, glycerin, potassium iodate, sorbitol, silica, cocoamidopropyl betaine, peppermint essence and purified water. The preparation method comprises the following steps of: (1) weighing; (2) adding the glacial acetic acid, the polysorbate-20, the glycerin and the purified water into the chitosan-iodine to be mixed uniformly and dissolved completely; (3) dissolving the potassium iodate with the purified water, and adding the dissolved potassium iodate into the mixture to mix uniformly; and (4) adding the sorbitol, the silica, the cocoamidopropyl betaine, the peppermint essence and the purified water and slowly mixing to obtain a finished product. The gel can kill various pathogenic microorganisms, restrains and kills pathogenic bacteria of oral cavities and throats and has the functions of stimulating wound healing, stopping bleeding and diminishing inflammation; and the gel also has effects in cleaning teeth and descaling, can quickly clean dental plaque and attached substances, does not have toxicity and oral mucosa stimulus and has a good stability. The processed gel is used for tooth-cleaning antimicrobial treatment on oral diseases such as periodontal disease and the like.
Description
technical field [0001] The invention relates to a medical dressing, in particular to a chitosan iodine-containing dressing, in particular to an antibacterial gel for cleaning teeth. Background technique [0002] Iodine has been used for body disinfection for 150 years, but due to the low solubility of iodine in water, it is only 1.315×10 at 25°C. -3 mol / L, it cannot be used as an aqueous preparation; it is easy to sublimate at room temperature, and the content is unstable; it is irritating to the skin and mucous membranes, which limits its wide application. At present, most of the widely used iodine disinfectants are based on organic polymers or surface active substances, and through the network structure or micelles formed between the carrier molecules, iodine is "bound" in it by the conformational effect of electrons and space. , thereby changing the free state of iodine in general iodine preparations, enhancing its stability and bactericidal effect, and reducing irritati...
Claims
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Application Information
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