Terbinafine hydrochloride cream and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN ยท China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- TIANSHENG PHARMA GROUP
- Publication Date
- 2015-05-20
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Abstract
Description
technical field
[0001] The invention relates to a cream for treating superficial mycosis of the skin, in particular to a terbinafine hydrochloride cream and a preparation method thereof. Background technique
[0002] Due to the wide application of antibiotics and the change of body immunity, there are more and more diseases caused by fungal infections. Since the first antifungal antibiotic amphotericin came out in 1955, the diagnosis of fungal diseases has become more and more perfect. The research and development of fungal drugs has also made great progress. At present, there are more than 80 kinds of antifungal drugs used clinically in the world.
[0003] Among them, terbinafine hydrochloride is an allylamine derivative and has broad-spectrum antifungal activity. It mainly inhibits fungal squalene cyclooxygenase, causing ergosterol deficiency and interfering with cell membrane integrity, so that fungi stop growing and play an antibacterial role; at the same time, squalene...