A kind of purposes of pharmaceutical composition

Abstract

The invention relates to application of drug composition in curing diseases of the respiratory system. The drug composition is obvious in effect of curing tracheaectasy concurrent infection caused by escherichia coli capable of producing beta-lactam enzyme, klebsiella pneumoniae and proteus mirabilis and bacterial pneumonia.

Description

technical field [0001] The present invention relates to the use of a pharmaceutical composition, in particular, the present invention relates to the use of a composition in preparing a medicament for treating tracheal dilatation complicated with infection and bacterial pneumonia. Background technique [0002] Compound 1 (shown in the following chemical formula) is a semi-synthetic antibiotic developed by Glaxo UK. Compound 2 (shown in the following chemical formula) is a semisynthetic β-lactamase inhibitor. Compound 2 combined with β-lactam antibiotics can increase the antibacterial activity of β-lactam antibiotics. [0003] [0004] Compound 1 Compound 2 [0005] In recent years, due to the irrational application of antibiotics, the resistance of bacteria to antibiotics is increasing. The increase of bacterial resistance makes the infection caused by drug-resistant bacteria difficult to control, resulting in an increase in infection mortality. Many antibiotics have a...

AI Technical Summary

Problems solved by technology

[0014] The existing public literature does not report the therapeutic effect of the composition, even if healthy people are used as subjects, the clinical trials of drug safety and tolerance have been investigated, and the therapeutic effect of the drug is affected by the absorption, transport and metabolism process in the human body. The impact is unpredictable. R&D experience shows that only 1-2 of tens of thousands of candidate drugs become marketable drugs, because there is a risk of failure in each R&D stage

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