Traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland as well as preparation method of traditional Chinese medicine composition

A technique for mammary gland hyperplasia and composition is applied in the field of traditional Chinese medicine preparations and their preparation, and the field of traditional Chinese medicine compositions for treating mammary gland hyperplasia diseases, which can solve the problems of unsatisfactory curative effect, few types of Chinese patent medicines, worrying side effects of western medicines, etc., and achieves good anti-mammary gland disease The effect of proliferation, large safety factor and stable process

Active Publication Date: 2013-06-12
重庆航月数云科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, among the medicines for the treatment of this disease, the side effects of western medicine are worrying, and traditional Chinese medicine is more commonly used, but there are very few Chinese patent medicines that can effectively relieve pain, and the curative effect is not satisfactory

Method used

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  • Traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland as well as preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland as well as preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland as well as preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 treats the Chinese medicine composition of mammary gland hyperplasia

[0036] Consists of the raw materials in the following proportions by weight:

[0037] Angelica 10, Pueraria 11, Cuscuta 18, Wangbuliuxing 22.5, Malt 15, Kelp 18, Yanhu 16, Tongcao 10;

[0038] Or: Angelica 15, Pueraria 15, Cuscuta 22.5, Wangbuliuxing 7.5, Malt 18, Kelp 14, Yanhu 22.5, Tongcao 8;

[0039] Or: Angelica 24, Pueraria 27, Cuscuta 10, Buliuxing 12, Malt 6, Kelp 9, Yanhu 14, Tongcao 15;

[0040] Or: Angelica 30, Pueraria 9, Cuscuta 7.5, Wangbuliuxing 18, Malt 9, Kelp 6, Yanhu 7.5, Tongcao 5;

[0041] Or: Angelica 20, Pueraria 18, Cuscuta 15, Buliuxing 15, Malt 12, Kelp 12, Yanhu 15, Tongcao 10.

Embodiment 2

[0042] Embodiment 2 treats the preparation of the extract of the Chinese medicine composition of hyperplasia of mammary gland disease

[0043] (1) Grinding the raw materials in proportions by weight as described in Example 1 into coarse powder respectively, and set aside;

[0044] (2) Take Chinese angelica coarse powder, soak in water, extract and collect volatile oil, collect filter residue I and aqueous solution and keep in another device;

[0045] (3) At 40-42°C, use β-cyclodextrin to clathrate the above-mentioned volatile oil and stir for 1-1.5 hours; then at 2-4°C, refrigerate for 8-12 hours, and filter the obtained After the clathrate is washed with a small amount of water and petroleum ether, it is dried at a temperature lower than 40°C for 8-10 hours, ground finely, passed through a 60-80 mesh sieve, and set aside;

[0046] (4) Add 6 to 10 times the amount of water to the filter residue I obtained in step (2), decoct for 1 to 2 hours, filter, collect the filtrate to o...

Embodiment 3

[0050] Embodiment 3 preparation of Chinese medicine granules containing the extract of the Chinese medicine composition for the treatment of mammary gland hyperplasia

[0051] Get the extract of the Chinese medicine composition for the treatment of mammary gland hyperplasia prepared in embodiment 2, add dextrin, starch and microcrystalline cellulose, wherein the mass ratio of the extract of dextrin, starch and microcrystalline cellulose and Chinese medicine composition is 0.2~0.4︰0.4~0.5︰0.4~0.6︰1, mix evenly, granulate, dry, pack separately, and then make traditional Chinese medicine granules.

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Abstract

The invention relates to a traditional Chinese medicine composition and preparation for treating proliferative diseases of mammary gland and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following bulk drugs in parts by weight: 10-30 parts of Chinese angelica, 9-27 parts of the root of kudzu vine, 7.5-22.5 parts of the seed of Chinese dodder, 7.5-22.5 parts of the seed of cowherb, 6-18 parts of malt, 6-18 parts of kelp, 7.5-22.5 parts of corydalis tuber and 5-15 parts of ricepaper pith. The invention also relates to an extractive of the traditional Chinese medicine composition treating proliferative diseases of mammary gland. The invention further relates to a traditional Chinese medicine preparation including the extractive of the traditional Chinese medicine composition for treating proliferative diseases of mammary gland and a preparation method of the traditional Chinese medicine preparation which is an oral preparation. The traditional Chinese medicine preparation consists of the extractive of the traditional Chinese medicine composition for treating proliferative diseases of mammary gland and common medicine auxiliary materials of the corresponding dosage form, has the pharmacological function of resisting hyperplasia of mammary gland, resisting inflammation, relieving pain, promoting blood circulation and removing blood stasis without bringing no side effects; and the traditional Chinese medicine preparation can be used for treating female hyperplasia of mammary gland, breast lump and breast distending pain and has low dosage of medication, thereby having good market prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and specifically relates to a traditional Chinese medicine composition for treating mammary gland hyperplasia, and also relates to a traditional Chinese medicine preparation composed of an extract of the traditional Chinese medicine composition for treating mammary gland hyperplasia and conventional pharmaceutical auxiliary materials and a preparation method thereof. Background technique [0002] Breast hyperplasia is a common breast disease in women, which can occur at any age after puberty. It is more common in women aged 25 to 45, with an incidence rate of 70% to 80%, ranking first among all types of breast diseases. The disease is essentially a disorder of the normal structure of the mammary gland caused by physiological hyperplasia and incomplete involution. The main clinical features are breast lumps and breast pain. Symptoms are usually aggravated during premenstrual p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P15/14
Inventor 姚干何宗玉
Owner 重庆航月数云科技有限公司
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