Medicine for treating dry eye syndromes

A dry eye disease and pharmaceutical technology, applied in the field of medicine, can solve the problems of large damage to eye tissue and drug resistance, and achieve the effect of clear curative effect and good safety.

Inactive Publication Date: 2014-02-05
顾克斌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the tissues of the eye are more sensitive, these drugs have greater damage to the eye tissues, and often cause problems of drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0012] Diagnostic criteria: eye dryness, foreign body sensation, fatigue, red eyes, photophobia, burning sensation, eye soreness, eye pain; tear function test: tear secretion test I (SCHERMER I) <10mm, tear film breakup time (BUT) <10s. Exclude photonous anemia, no lacrimal gland, lacrimal duct obstruction caused by extensive ocular surface damage due to neurological disorders, uncontrolled systemic diseases, wearing contact lenses, recent history of eye surgery or trauma, etc. Systemic antihistamines, anticholinergics or other ophthalmic drugs are contraindicated during the medication.

[0013] Fifty patients with dry eye syndrome who met the above diagnostic criteria were selected, including 25 males and 25 females, with an average age of 37 years.

[0014] Use the decoction prepared in Example 1 for treatment, 2 times a day, each oral administration of 50 milliliters. One week of treatment is a course of treatment. Review after 1 week of treatment. The Schirmer test and...

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PUM

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Abstract

The invention relates to a medicine for treating dry eye syndromes. The medicine for treating dry eye syndromes comprises the following components in parts by weight: 5-10 parts of radix scrophulariae, 10-20 parts of dried ginger, 20-30 parts of dogwood, 10-20 parts of platycodon grandiflorum, 15-25 parts of angelica dahurica, 5-15 parts of inula flower, 10-30 parts of cowherb seed, 1-15 parts of motherwort fruit, 10-20 parts of radix sileris, 15-30 parts of capillary artemisia, 20-30 parts of myrobalan, 1-20 parts of fenugreek, 1-20 parts of celandine, 10-25 parts of rhizoma imperatae, 10-30 parts of cocklebur fruit, 1-20 parts of emblic leafflower fruit, 15-20 parts of kamuning, 10-20 parts of semen pharbitidis, 15-20 parts of lychee seed, 15-30 parts of glabrous sarcandra herb, 10-20 parts of clinopodium polycephalum, 10-25 parts of folium sennae, 5-15 parts of aleppo avens, 1-20 parts of uniflower swisscentaury root, 15-25 parts of folium rhododendri daurici, 15-25 parts of potentilla discolor, 10-20 parts of calyx seu fructus physalis, 15-25 parts of white mulberry root-bark, 20-30 parts of lindley eupatorium, 1-20 parts of gorgon euryale seed and 10-25 parts of Chinese azalea flower. All the components of the medicine for treating dry eye syndromes are natural materials, so that the medicine for treating the dry eye syndromes has good safety and clear curative effect and is suitable for large-scale application in clinic.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicament for treating dry eye. Background technique [0002] Dry eye syndrome refers to a group of diseases that cause eye discomfort symptoms due to tear film instability and ocular surface damage caused by abnormal tear quantity or quality or abnormal tear fluid dynamics. The clinical manifestations are dryness, foreign body sensation, burning Sensation, itching, photophobia, red eyes, blurred vision, fluctuations in vision and visual fatigue. With the development of social economy and the improvement of people's living standards, the incidence of dry eye tends to increase and tend to become younger. At present, eye drops and the like are used clinically to treat dry eye syndrome. Since the tissues of the eye are relatively sensitive, these drugs have relatively large damage to the eye tissues, and often cause problems of drug resistance. Contents of the invention [0003] The ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P27/02
Inventor 顾克斌
Owner 顾克斌
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