Traditional Chinese medicine composition and preparation method thereof

A technology of composition and natural medicine, applied in the direction of drug combination, pharmaceutical formula, anti-tumor drugs, etc., can solve the problems of dehydration, acid-base balance disorder, malnutrition, etc., to increase the inhibitory effect, enhance the inhibitory effect, and achieve good synergy effect of action

Inactive Publication Date: 2013-07-03
张宗升
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition and preparation method thereof
  • Traditional Chinese medicine composition and preparation method thereof

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Experimental program
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Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of Concentrated Extract of Astragalus and White Wood Perfume Decoction

[0036] According to the compatibility ratio of 1:1 or 1-4:1, take astragalus and white woody incense, 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate and medicinal residue Add 6 times more distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of astragalus polysaccharide

[0038] Astragalus is crushed, saponin is extracted with 95% ethanol and dried, then distilled water is added, saturated lime water is added drop by drop, the pH value is adjusted, the material is left ...

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Abstract

The invention relates to a natural medicine composition, a preparation method thereof, and an application of the composition in preparation of a toxicity reducing and efficacy enhancing medicine for cancer chemotherapy. The natural medicine composition is composed of an astragalus and aquilaria sinensis extract after water decoction and concentration, astragalus polysaccharide, an aquilaria sinensis chloroform extract and an aquilaria sinensis hexane extract in a ratio of (1-4): (5-8): (1-5): (4-8). The composition has an excellent curative effect on diarrhea related with the cancer chemotherapy, and can enhance the effect on the cancer chemotherapy simultaneously.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of astragalus and whitewood fragrant decoction concentrated extract, astragalus polysaccharide, whitewood chloroform extract and whitewood hexane extract, the natural medicine The preparation method of the composition and the use of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P1/12A61P35/00A61K36/481A61K31/715
Inventor 张宗升
Owner 张宗升
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