Pharmaceutical composition for treating pediatric esophageal achalasia

A technology for achalasia and a composition, which is applied in the field of traditional Chinese medicine, can solve the problems of lack of achalasia in children, pain and high compliance in children, and high recurrence rate, so as to reduce the types and dosages of drugs, increase the burden on the liver and kidney, and reduce the burden on the liver and kidneys. Powerful effect

Inactive Publication Date: 2015-02-25
牟丽萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs are not suitable for use in pediatrics, so now more endoscopic balloon dilation is used, but dilation often requires multiple times to achieve relief, and the recurrence rate is high, and children with severe pain have poor compliance
Therefore, there is currently a lack of medical treatment drugs for children with achalasia.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1, the weight ratio of raw materials: Muhe 20g, Kapok bark 10g, Poria cocos 6g, Tangerine peel 10g, Artemisia argyi root 6g, Scorpio vine 10g, Pueraria radiata 10g, Aescin 10g, Loofah 12g, Gourilla 2g , burnt malt 6g, burnt grain sprouts 20g.

[0029] The preparation method of Example 1 is: mix Muhe, kapok bark, Poria cocos, tangerine peel, Artemisia annua root, stellite vine, kudzu root, aescin, towel gourd, Jiulixiang, scorched malt and scorched grain buds, add water and decoct, 30 After 2 minutes, take the filtrate, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide it into two parts and take it in the morning and evening.

Embodiment 2

[0030] Example 2, the weight ratio of raw materials: 10 parts of Muhe, 6 parts of kapok bark, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of Artemisia annua root, 6 parts of terrazzo vine, 6 parts of kudzu root, 6 parts of aescin , 6 parts of loofah, 1 part of Jiulixiang, 3 parts of burnt malt, and 10 parts of burnt grain sprouts.

Embodiment 3

[0031] Example 3, the weight ratio of raw materials: 20 parts of Muhe, 10 parts of kapok bark, 6 parts of Poria cocos, 10 parts of tangerine peel, 6 parts of Artemisia annua root, 10 parts of terrazzo, 10 parts of kudzu root, 10 parts of Aescin , 10 parts of loofah, 2 parts of Jiulixiang, 6 parts of burnt malt, and 20 parts of burnt grain sprouts.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating pediatric esophageal achalasia. The pharmaceutical composition is applied to the treatment of pediatric esophageal achalasia. The pharmaceutical composition is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: fingerleaf rodgersflower rhizome, bombax malabaricum peel, poriacocos (Schw.) Wolf, luffa cylindrica (L.) Roem., murraya jasminorage, hordeum vulgare L., setaria italica (L.) Beauv., citrus reticulata Blanco, artemisia japonica Thunb., trachelospermum jasminoides (Lindl.) Lem., radix puerariae and paris polyphylla Sm.. Proved by clinical trials, the pharmaceutical composition has the characteristics of good treatment effect and high safety in the treatment of pediatric esophageal achalasia, so that the pharmaceutical composition is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating children with achalasia. Background technique [0002] Pediatric achalasia (esophageal achalasia) is an esophageal motility disorder, which refers to a disease in which there is no peristalsis in the esophageal body after swallowing and poor relaxation of the cardiac sphincter. It is characterized by impaired relaxation of the lower esophageal sphincter (LES) during swallowing, and lack of peristaltic contraction of the smooth muscle segment of the esophagus, resulting in functional esophageal obstruction. The cause of this disease is unknown. It may be related to toxins, nutritional deficiencies, genes and local inflammation. Clinical studies have found that mental concerns can aggravate children's symptoms. Consider whether cortical nerve dysfunction is caused by mental stimulation, leading to central and autonomic nervous...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P1/00
Inventor 牟丽萍
Owner 牟丽萍
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