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Pharmaceutical composition for treating esophageal achalasia

Achalasia and composition technology, applied in the field of traditional Chinese medicine, can solve the problems of patients with great pain, high recurrence rate, and poor compliance, and achieve the effects of relieving clinical symptoms, strong dispersing ability, and improving poor coordination of relaxation and relaxation

Inactive Publication Date: 2013-07-10
朱明莉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the clinical curative effect of the above-mentioned drugs is below 50%, and more patients have to undergo surgical treatment. The less invasive method is endoscopic balloon dilation, but dilation often requires multiple times to achieve remission, and the recurrence rate is high. Great pain and poor compliance
Therefore, there is currently a lack of a clinically effective medical treatment drug for esophageal achalasia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1, the weight ratio of raw materials: Muhe 20g, Usnea 10g, Poria cocos 6g, Tangerine peel 10g, Artemisia annua root 6g, Trichonia vine 10g, Pueraria lobata 10g, Aescin 10g, loofah 12g, Jiulixiang 2g , burnt malt 6g, burnt grain sprouts 20g.

[0029] The preparation method of Example 1 is: mix and decoct Muhe, Usnea, Poria, Tangerine Peel, Artemisia annua Root, Caterpillar, Pueraria, Aescin, Loofah, Gurixiang, Scorched Malt, and Scorched Valley Buds in water for 30 After 2 minutes, take the filtrate, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide it into two parts and take it in the morning and evening.

Embodiment 2

[0030] Example 2, weight ratio of raw materials: 10 parts of Muhe, 6 parts of Usnea, 3 parts of Poria cocos, 6 parts of dried tangerine peel, 3 parts of Artemisia annua root, 6 parts of Poria vine, 6 parts of Pueraria lobata, 6 parts of Aescin , 6 parts of loofah, 1 part of Jiulixiang, 3 parts of burnt malt, and 10 parts of burnt grain sprouts.

Embodiment 3

[0031] Example 3, the weight ratio of raw materials: 20 parts of Muhe, 10 parts of Usnea, 6 parts of Poria cocos, 10 parts of dried tangerine peel, 6 parts of Artemisia annua root, 10 parts of terrazzo vine, 10 parts of kudzu root, 10 parts of Aescin , 10 parts of loofah, 2 parts of Jiulixiang, 6 parts of burnt malt, and 20 parts of burnt grain sprouts.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating esophageal achalasia. The pharmaceutical composition is applied to the treatment of esophageal achalasia. The pharmaceutical composition is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: fingerleaf rodgersflower rhizome, usnea diffracta Vain., poriacocos (Schw.) Wolf, luffa cylindrica (L.) Roem., murraya jasminorage, hordeum vulgare L., setaria italica (L.) Beauv., citrus reticulata Blanco, artemisia japonica Thunb., trachelospermum jasminoides (Lindl.) Lem., radix puerariae and paris polyphylla Sm.. Proved by clinical trials, the pharmaceutical composition has the characteristics of good treatment effect and high safety in the treatment of esophageal achalasia, so that the pharmaceutical composition is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating esophageal achalasia. Background technique [0002] Esophageal achalasia is a primary total esophageal motility disorder characterized by ① no peristalsis in the esophageal body. ② When swallowing, the lower esophageal sphincter does not relax or does not relax completely. ③The lower esophageal sphincter pressure increases at rest. Although achalasia is a benign disease, it has a great impact on quality of life, health and longevity. Due to dysphagia, patients can use all measures, including body position, drinking water, repeated swallowing and other measures, so that patients are ashamed to eat in front of everyone and prefer to eat alone, causing psychological pressure and seriously affecting social activities. The cause of this disease is unknown. It may be related to toxins, nutritional deficiencies, genes and local in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61K9/48A61P1/00
Inventor 朱明莉徐承棉乔爱芹
Owner 朱明莉