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Lipid Supplementation for Maintaining Health and Treating Acute and Chronic Diseases
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A health and phospholipid technology, applied in metabolic diseases, skin diseases, blood diseases, etc., to achieve the effect of increasing absorption and increasing bioavailability
Inactive Publication Date: 2016-05-18
ALLERGY RES GRP
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Embodiment 1
[0232] The starting material is commercially available lecithin (Wheat species).
[0233] The number of phospholipids identified is listed in Table 11 below. Row A lists the amount, expressed in mg, of phospholipids measured in the starting material. The starting material is boiled, cooled and the liquid phase is separated from the solid residue. Rows B to G show the composition of the starting material after extraction using various solvent combinations. Row B lists the concentrations of various measured phospholipids obtained by ethanol extraction in the liquid phase. Row C begins by listing the various measured phospholipid concentrations recovered in the solid phase by hexane extraction. In a similar manner, row D shows the extraction results of the liquid phase using ethanol / glycerol solution, and row E shows the concentration of the solid phase after ethanol / glycerol extraction. Rows F and G show the liquid and solid phase results after ethanol / α-lipoic acid extracti...
Embodiment 2
[0260] As mentioned above, the same procedure was repeated with the same starting material (commercially available lecithin), but with different extracts (or different concentrations).
[0261] Tables 15 and 16 list the amount (grams) and percentage of each phospholipid in each extraction.
[0291] Extracts of Chlorella, Spirulina, and Lecithin with Spirulina1
[0292]
[0293] 7A. Chlorella
[0294] 8A. Spirulina
[0295] 9A. Lecithin 1 plus Spirulina
[0296] 7B. Chlorella
[0297] 8B. Spirulina
[0298] 9B. Lecithin 1 plus Spirulina
[0299] Based on the data in Tables 19 and 20, it was deduced that the major phospholipid of Spirulina is PG, but the total lipid content and the conformation of lipid acyl groups indicated that Spirulina was only a less preferred lipid source. Further co-extraction of Spirulina and Lecithin 1 did not show any evidence of lipid turnover.
[0300]In the first extract, Chlorella produced n...
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Abstract
Nutritional supplement formulations suitable for enhancement of specific cellular and mitochondrial functions, including enriched formulations of phospholipids and chemical precursors, containing specifically defined concentrations of phosphatidylglycerol, phosphatidic acid, lecithin, and mitochondrial and cell membrane phospholipid molecules and other desirable Element. Methods for enriched extraction of cellular and mitochondrial membrane molecules and precursors from microbial, plant, and other sources are also presented. The formulation can be combined with nutrients, prebiotics and probiotic (microbial) factors to increase bioavailability through the digestive tract and increase absorption at the cellular and subcellular levels. These lipid combinations can be used to treat mitochondrial diseases associated with medical pathologies, chronic diseases and syndromes, or to maintain lipid balance for normal mitochondrial function, and be administered in various forms. The various combinations are particularly enriched in the correct phospholipids and the correct fatty acid residues, which can be used to treat organs, tissues, cells and systems.
Description
[0001] This application claims the benefit of US Provisional Application 61 / 373,178, filed August 12, 2010. [0002] Nutrient-enriched supplements are described as including essential ingredients to maintain (or repair) cellular and mitochondrial health. Membrane essential molecules and chemical precursors for these molecules are provided in supplement form suitable for lipid replacement therapy. The procedures and formulations presented herein are designed to add and supplement lipids in cells including, but not limited to, phosphatidylglycerol (PG), lecithin (PC), phosphatidylethanolamine (PE), phosphatidylglycerolSerine (PS), phosphatidic acid (PA) and related phosphorylated- and sugar-phospholipids (containing linoleic acid (LA), other healthy fatty acids and phospholipid (PI) precursors. In addition, by controlling or modifying lipid source plants or growth conditions of microorganisms (lipid source materials), selecting specific species to produce the desired lipids, pur...
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