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Method for measuring influences of imbedding 125I particle source in support or catheter on dose distribution

A technology of dose distribution and particle source, which is applied in the direction of X-ray/γ-ray/particle irradiation therapy, can solve the problems of inconsistent and incomplete agreement of experimental results, and achieve the effect of small environmental impact, accurate and reliable method, and high sensitivity

Inactive Publication Date: 2013-10-09
TECHN PHYSICS INST HEILONGJIANG ACADOF SCI
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  • Summary
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, many scholars at home and abroad have conducted research on whether metal stents and particle catheters in the target area affect the distribution of radiation dose and to what extent. The requirement of "the total uncertainty of the dose in the target area is less than 5%" stipulated in the No.

Method used

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  • Method for measuring influences of imbedding 125I particle source in support or catheter on dose distribution
  • Method for measuring influences of imbedding 125I particle source in support or catheter on dose distribution

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Experimental program
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specific Embodiment approach 1

[0015] Specific implementation mode one: measurement in this implementation mode 125 The method for implanting stents or catheters with I particle source on dose distribution is carried out according to the following steps:

[0016] One, use 241 The Am standard source performs energy calibration and dose calibration for the thermoluminescence dose detector;

[0017] 2. Make a solid cylinder with plexiglass with a CT value of 1, as a tumor equivalent model, the size of the model is 70mm in diameter x 100mm in height;

[0018] 3. Machining a cylinder hole at the center of the upper surface of the tumor equivalent model, the centerline of the cylinder hole coincides with the centerline of the tumor equivalent model;

[0019] 4. Symmetrically process 4 round holes or 4 square holes on a circle with the center of the upper surface of the tumor equivalent model as the center and a radius of 5-25 mm;

[0020] 5. Put the 4 thermoluminescent dose detectors calibrated in step 1 into ...

specific Embodiment approach 2

[0021] Embodiment 2: This embodiment is different from Embodiment 1 in that: in step 4, the radius is 10-20 mm. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0022] Embodiment 3: The difference between this embodiment and Embodiment 1 is that in step 4, the radius is 15 mm. Others are the same as in the first embodiment.

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Abstract

The invention discloses a method for measuring influences of imbedding a 125I particle source in a support or a catheter on dose distribution, and relates to a method for measuring of the influences of imbedding the particle source in the support or the catheter on the dose distribution. The method for measuring the influences of imbedding of the 125I particle source in the support or the catheter on the dose distribution comprises the steps of firstly, using a standard source for energy calibration and dose calibration on thermoluminescence dose detectors, secondly, making a tumor equivalent model, thirdly, machining cylindrical holes in the center position of the upper surface of the model, fourthly, symmetrically machining holes in a circle with the center of the upper surface of the model as the center of the circle, fifthly, putting the detectors after the calibration into the holes machined in the step four, putting the 125I particle source into the catheter or the support, then putting the catheter or the support on the cylindrical holes machined in the step three, conducting irradiation, then taking out the 125I particle source, respectively measuring measured values x of the detectors, and calculating the adsorbed dose according to the formula. The method is used for measuring the influences of imbedding the 125I particle source in the support or the catheter on the dose distribution.

Description

technical field [0001] The invention relates to a method for measuring the influence of particle sources placed in stents or catheters on dose distribution. Background technique [0002] Malignant tumors pose a huge threat to human health and life. Its treatment has become one of the two major problems in medicine. Worldwide, it has constituted the second leading cause of human death from disease. Among the world's population, about 8 million people are newly diagnosed with malignant tumors every year, and more than 5 million people die of malignant tumors. Almost every 6 seconds, one patient with malignant tumors dies. In my country, about 1.7 million people are newly diagnosed with malignant tumors every year, and about 800,000 people die of malignant tumors every year. [0003] The main treatment methods for malignant tumors include surgery, radiotherapy (referred to as radiotherapy), and chemotherapy. Brachytherapy is one of the important methods of radiotherapy for ...

Claims

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Application Information

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IPC IPC(8): A61N5/10
Inventor 张慧周巍关世荣梅雪松王振超庞杨韩业辉
Owner TECHN PHYSICS INST HEILONGJIANG ACADOF SCI
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