Pharmaceutical composition with whitening action as well as preparation method and application thereof
A composition and drug technology, applied in the field of skin care products, can solve problems such as aggravation of skin problems and skin discomfort, and achieve the effects of less irritation, good inhibitory effect, and inhibitory activity
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Embodiment 1
[0042] A pharmaceutical composition with whitening effect in this embodiment, its raw material formula is composed of the following components in parts by weight:
[0043] 30 parts of traditional Chinese medicine extract;
[0044] Coenzyme Q10 10 parts;
[0045] Vitamin E 8 parts.
[0046] Above-mentioned coenzyme Q10 and vitamin E are all commercially available products.
[0047] In the raw material formula of the above-mentioned pharmaceutical composition, the raw material formula of the Chinese medicine extract is composed of the following components in parts by weight:
[0048] Sophora flavescens 20 parts;
[0049] 13 parts purslane;
[0050] 8 parts ebony;
[0051] Fructus Cnidii 7 servings.
[0052] The preparation method of the above-mentioned Chinese medicine extract comprises the following steps:
[0053] Step 1. Grind the ebony plum and soak it in an acetic acid solution with a concentration of 1mol / L for 12 hours, then filter and collect the filter residue; t...
Embodiment 2
[0059] A pharmaceutical composition with whitening effect in this embodiment, its raw material formula is composed of the following components in parts by weight:
[0060] 25 parts of traditional Chinese medicine extract;
[0061] Coenzyme Q10 12 parts;
[0062] Vitamin E 5 parts.
[0063] Above-mentioned coenzyme Q10 and vitamin E are all commercially available products.
[0064] In the raw material formula of the above-mentioned pharmaceutical composition, the raw material formula of the Chinese medicine extract is composed of the following components in parts by weight:
[0065] Sophora flavescens 16 parts;
[0066] 12 parts purslane;
[0067] 13 parts ebony;
[0068] Fructus Cnidii 5 servings.
[0069] The preparation method of the above-mentioned Chinese medicine extract comprises the following steps:
[0070] Step 1. Grind the ebony plum and soak it in an acetic acid solution with a concentration of 1mol / L for 12 hours, then filter and collect the filter residue; th...
Embodiment 3
[0075] Example 3 Research on Inhibition of Tyrosinase
[0076] A. Experimental samples
[0077] The present embodiment is divided into three sample groups, specifically as follows:
[0078] 1. Sample 1: the pharmaceutical composition prepared in Example 1;
[0079] 2. Sample 2: the pharmaceutical composition prepared in Example 2;
[0080] 3. Sample 3: the pharmaceutical composition of sample 3, its formula is in parts by weight, consisting of 25 parts of Chinese medicine extract, 12 parts of coenzyme Q10 and 5 parts of vitamin E, the raw material formula of the Chinese medicine extract is in parts by weight It is composed of 16 parts of Sophora flavescens, 12 parts of purslane, 13 parts of black plum and 5 parts of Cnidium; the preparation method of the pharmaceutical composition of sample 3 is:
[0081] Grind Sophora flavescens, Purslane chinensis, Ume and Fructus Cnidii respectively, mix to obtain a mixture of Chinese medicinal materials, and use the mixture of Chinese...
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