Method and device for detecting transparency of tissue engineered cornea

Abstract

The invention relates to a detection method and device for the transparency of a tissue engineering cornea. The detection device comprises a hardware part and a software part, wherein the hardware part is composed of a control unit, a tissue engineering cornea detection executing unit, a signal transmission unit and a power supply unit. The control unit comprises an industrial personal computer which is internally inserted with a data acquisition card. The tissue engineering cornea detection executing unit comprises two illumination sensors, two metal boxes, a semi-transparent and semi-reflecting light splitting sheet, a metal box body with a drawer type cover, a small-sized semiconductor laser device and a light splitting sheet optical bracket. The signal transmission unit comprises a data cable, a junction box and an illumination sensor cable. The power supply unit comprises a power line, a 220V-to-12-24V 50W direct current switch power supply and a special power supply adapter for the small-sized semiconductor laser device. The detection device for the transparency of the tissue engineering cornea is simple and practical, high in measurement sensitivity, high in precision and strong in universality, can automatically store data and conveniently store the data and is stable in performance.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and relates to a tissue engineering corneal transparency detection method and device. Background technique [0002] Due to the extreme shortage of corneal donors, most corneal blind patients cannot receive timely and effective surgical treatment, which brings great pressure and burden to patients, families and society. The development and application of tissue-engineered corneas have received more and more attention from researchers and clinicians. Theoretically, using tissue engineering technology to reconstruct tissue-engineered cornea has the following advantages: (1) only a small amount of healthy corneal tissue can be obtained and tissue engineering technology can be used to construct a graft of sufficient size; (2) for For patients with residual healthy corneas, they can completely reconstruct the cornea with cells from healthy corneal tissue (or even use tissue puncture to achieve th...

AI Technical Summary

Problems solved by technology

[0003] The transparency of tissue-engineered cornea is an important indicator of the quality of tissue-engineered cornea, which is directly related to whether tissue-engineered cornea can enter clinical application. Transparency detectors for detecting transparent materials such as glass and liquid range from one to two thousand to tens of thousands. The price is cheap, and its measurement performance, stability, and accuracy cannot be guaranteed, and we know that it is easy to be affected by various Interference affects the detection accuracy. The traditional method of detecting light intensity is generally realized through hardware circuits, but this method has problems such as complex circuits, long development time, relatively high cost, and unstable performance. The DR81 / 82 transparency detector The core principle is that the ratio of the luminous flux passing through the object to the luminous flux incident on the object is the light transmittance of the object. This series of transparency detectors is mainly used to measure the visible light transmittance of various glass, plastic, film and transparent or translucent materials. , which is composed of a light source, a luminous flux sensor, a hardware circuit board and a liquid crystal display. The external light intensity of the device has a certain influence on it during use, unless it is detected in a dark environment, and its working power is a battery. When the battery When the power drops, it will definitely affect the luminous flux of the incident object, but the instrument still works according to the originally set rated incident luminous flux, which will lead to an increase in the error of the detection result. will lead to the above problems

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