Detection method and device for transparency of tissue engineering cornea

A tissue engineering and detection device technology, applied in the field of biomedical engineering, can solve problems such as stability, accuracy cannot be guaranteed, error in detection results increases, performance is not stable enough, etc., to achieve strong scalability, stable performance, and reduced research and development. effect of cycles

Active Publication Date: 2014-01-22
HANGZHOU BAIQIAO MEDICAL TECH CO LTD
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Problems solved by technology

[0003] The transparency of tissue-engineered cornea is an important indicator of the quality of tissue-engineered cornea, which is directly related to whether tissue-engineered cornea can enter clinical application. Transparency detectors for detecting transparent materials such as glass and liquid range from one to two thousand to tens of thousands. The price is cheap, and its measurement performance, stability, and accuracy cannot be guaranteed, and we know that it is easy to be affected by various Interference affects the detection accuracy. The traditional method of detecting light intensity is generally realized through hardware circuits, but this method has problems such as complex circuits, long development time, relatively high cost, and unstable performance. The DR81 / 82 transparency detector The core principle is that the ratio of the luminous flux passing through the object to the luminous flux incident on the object is the light transmittance of the object. This series of transparency detectors is mainly used to measure the visible light transmittance of various glass, plastic, film and transparent or translucent materials. , which is composed of a light source, a luminous flux sensor, a hardware circuit board and a liquid crystal display. The external light intensity of the device has a certain influence on it during use, unless it is detected in a dark environment, and its working power is a battery. When the battery When the power drops, it will definitely affect the luminous flux of the incident object, but the instrument still works according to the originally set rated incident luminous flux, which will lead to an increase in the error of the detection result. will lead to the above problems

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  • Detection method and device for transparency of tissue engineering cornea

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Embodiment Construction

[0021] The present invention will be further described below in conjunction with accompanying drawing.

[0022] Based on the optical definition of transparency in geometric optics, the present invention designs and develops a set of method and device for measuring the transparency of tissue engineering cornea. According to the definition of optical transparency (hereinafter referred to as transparency), a beam of parallel light propagates for distance After that, as long as the propagation distance can be measured Front and rear luminous energy flow and The transparency value of the tissue-engineered cornea can be calculated, and the transparency can be directly converted into the illuminance correlation formula obtained by the illuminance sensor by using the transparency mathematical model, which provides a new method for the research of tissue-engineered cornea in the field of biomedical engineering . Using the labview technology as the core, the tissue enginee...

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Abstract

The invention relates to a detection method and device for the transparency of a tissue engineering cornea. The detection device comprises a hardware part and a software part, wherein the hardware part is composed of a control unit, a tissue engineering cornea detection executing unit, a signal transmission unit and a power supply unit. The control unit comprises an industrial personal computer which is internally inserted with a data acquisition card. The tissue engineering cornea detection executing unit comprises two illumination sensors, two metal boxes, a semi-transparent and semi-reflecting light splitting sheet, a metal box body with a drawer type cover, a small-sized semiconductor laser device and a light splitting sheet optical bracket. The signal transmission unit comprises a data cable, a junction box and an illumination sensor cable. The power supply unit comprises a power line, a 220V-to-12-24V 50W direct current switch power supply and a special power supply adapter for the small-sized semiconductor laser device. The detection device for the transparency of the tissue engineering cornea is simple and practical, high in measurement sensitivity, high in precision and strong in universality, can automatically store data and conveniently store the data and is stable in performance.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and relates to a method and a device for detecting transparency of tissue engineering cornea. Background technique [0002] Due to the extreme shortage of corneal donors, most patients with corneal blindness cannot receive timely and effective surgical treatment, which brings great pressure and burden to patients, families and society. The development and application of tissue engineered cornea has attracted more and more attention from researchers and clinicians. Theoretically, the advantages of using tissue engineering technology to reconstruct the tissue engineered cornea are as follows: (1) Only a small amount of healthy corneal tissue is needed to construct a graft of sufficient size by applying tissue engineering technology; (2) For For patients with residual healthy corneas, it is entirely possible to obtain corneal tissue cells from healthy parts to reconstruct the cornea (or even u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/17
Inventor 李宏
Owner HANGZHOU BAIQIAO MEDICAL TECH CO LTD
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