Eye fatigue suppression composition and food and drink containing same

A technology for eye fatigue and composition, applied in the field of compositions for relieving eye fatigue, to achieve the effects of relieving eye fatigue, high safety and good impression

Inactive Publication Date: 2014-03-12
LOTTE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these documents specifically exemplify the effects of long-term administration to patients with diseases such as glaucoma and macular degeneration, and the effects of direct injection or instillation into the eyes, and there is no description of simple and immediate solutions to eye fatigue. or imply

Method used

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  • Eye fatigue suppression composition and food and drink containing same
  • Eye fatigue suppression composition and food and drink containing same
  • Eye fatigue suppression composition and food and drink containing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Determination of the effect of resveratrol on eye fatigue

[0056]

[0057] As resveratrol, VINEATROL (registered trademark) WD manufactured by Sunburite Co., Ltd. was used. The preparation contains 0.30% resveratrol (analytical value) in a glycerin formulation. When taking each time, distill 2 g of the glycerin preparation (containing 6 mg of resveratrol) to 10 ml with distilled water.

[0058] As black currant anthocyanins, "Kashisu Ekis-35" (powder) manufactured by Tama Biochemical Co., Ltd. was used. The total content of delphinidin-3-rutinoside, cyanidin-3-rutinoside, delphinidin-3-glucoside, and cyanidin-3-glucoside in this powder It is more than 35.0% (standard value). When taking each time, according to the conditions that the total amount of the above four kinds reaches 35.0% and contains 50 mg anthocyanins, dilute 142.9 mg powder to 10 ml with distilled water.

[0059] Of all the three subjects, two were provided with a control period of 18 days, a resve...

Embodiment 2

[0086] Confirmation of the concentration dependence of the effect of resveratrol on eye fatigue

[0087]

[0088] A control period of 5 days, a 3 mg resveratrol intake period of 5 days, and a 1 mg resveratrol intake period of 5 days were set for 2 test subjects. During this test period, the same measurement as in Example 1 was carried out every evening. However, unlike Example 1, water was absorbed in the oral cavity during the control period.

[0089] When taking resveratrol once, dilute 1g of glycerin preparation (containing 3mg of resveratrol) or 0.33g (containing 1mg of resveratrol) to 10ml with distilled water.

[0090]

[0091] Compared with the control, which is the case of oral absorption of water, and compared the effect on eye fatigue obtained by oral absorption of 1 and 3 mg resveratrol, the results of peripoint measurement of 2 subjects for 5 times in each period As shown in Table 5. Graph this as image 3 .

[0092] table 5

[0093]

[0094] The resul...

Embodiment 3

[0109] Confirmation of Oral Absorption of Resveratrol by Oral Absorption Test

[0110]In order to confirm the absorption of resveratrol in the oral cavity, an oral absorption test was performed to investigate the residual rate of resveratrol in the spit out solution after stirring the resveratrol solution in the oral cavity with the tongue and cheeks for a certain period of time without drinking it. .

[0111]

[0112] According to the condition that the intake of resveratrol reaches 1 or 2 mg per dose, weigh the required amount of resveratrol preparation, add 5 mM phosphate buffer solution (pH6.5) warmed to 37°C to make up to volume to 10 ml to prepare a test solution. Subjects (2) rinsed their mouths with distilled water and remained silent for 5 minutes. Thereafter, 10 ml of the above-mentioned test solution was contained in the mouth, and stirred with the cheeks and tongue at a speed of once / 1 second for a certain period of time without drinking. Spit out the solution...

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Abstract

The present invention provides an eye fatigue suppression composition having resveratrol as an active ingredient. As a result of extensive research, the inventors of the present invention discovered that resveratrol has an eye fatigue suppression effect and brought to fruition this eye fatigue suppression composition having resveratrol as an active ingredient. This composition is absorbed through the oral cavity and acts immediately to suppress eye fatigue.

Description

technical field [0001] The present invention relates to a composition for alleviating eye fatigue and food and drink containing the composition. The present invention further relates to the above-mentioned composition, which has an immediate effect on eye fatigue and is administered in a form absorbed by the oral cavity, and a food or drink containing the composition. Background technique [0002] Regarding eyestrain, reports of the EMF Professional Committee of the Association of Electronics and Information Technology Industries (Non-Patent Documents 1 and 2) describe as follows. Eye fatigue refers to general eye fatigue such as heavy eyelids and blurred vision, which can be recovered in a short period of time by taking a certain amount of rest. Accumulation of eye fatigue can progress to optic nerve fatigue. Optic nerve fatigue is a morbid state of fatigue that does not recover even with rest. Prolonged use of eyes can cause discomfort, pressure, headache, vision loss, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/05A23L1/30A23L2/52A61P27/02A23G3/34A23G4/00
CPCA23G3/48A23L1/3002A23G4/068A61K31/05A23L33/105A61P27/00A61P27/02
Inventor 安藤绘美子安藤智教吉田圭司郎志村进
Owner LOTTE CO LTD
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