Eye fatigue suppression composition and food and drink containing same
A technology for eye fatigue and composition, applied in the field of compositions for relieving eye fatigue, to achieve the effects of relieving eye fatigue, high safety and good impression
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Embodiment 1
[0055] Determination of the effect of resveratrol on eye fatigue
[0056]
[0057] As resveratrol, VINEATROL (registered trademark) WD manufactured by Sunburite Co., Ltd. was used. The preparation contains 0.30% resveratrol (analytical value) in a glycerin formulation. When taking each time, distill 2 g of the glycerin preparation (containing 6 mg of resveratrol) to 10 ml with distilled water.
[0058] As black currant anthocyanins, "Kashisu Ekis-35" (powder) manufactured by Tama Biochemical Co., Ltd. was used. The total content of delphinidin-3-rutinoside, cyanidin-3-rutinoside, delphinidin-3-glucoside, and cyanidin-3-glucoside in this powder It is more than 35.0% (standard value). When taking each time, according to the conditions that the total amount of the above four kinds reaches 35.0% and contains 50 mg anthocyanins, dilute 142.9 mg powder to 10 ml with distilled water.
[0059] Of all the three subjects, two were provided with a control period of 18 days, a resve...
Embodiment 2
[0086] Confirmation of the concentration dependence of the effect of resveratrol on eye fatigue
[0087]
[0088] A control period of 5 days, a 3 mg resveratrol intake period of 5 days, and a 1 mg resveratrol intake period of 5 days were set for 2 test subjects. During this test period, the same measurement as in Example 1 was carried out every evening. However, unlike Example 1, water was absorbed in the oral cavity during the control period.
[0089] When taking resveratrol once, dilute 1g of glycerin preparation (containing 3mg of resveratrol) or 0.33g (containing 1mg of resveratrol) to 10ml with distilled water.
[0090]
[0091] Compared with the control, which is the case of oral absorption of water, and compared the effect on eye fatigue obtained by oral absorption of 1 and 3 mg resveratrol, the results of peripoint measurement of 2 subjects for 5 times in each period As shown in Table 5. Graph this as image 3 .
[0092] table 5
[0093]
[0094] The resul...
Embodiment 3
[0109] Confirmation of Oral Absorption of Resveratrol by Oral Absorption Test
[0110]In order to confirm the absorption of resveratrol in the oral cavity, an oral absorption test was performed to investigate the residual rate of resveratrol in the spit out solution after stirring the resveratrol solution in the oral cavity with the tongue and cheeks for a certain period of time without drinking it. .
[0111]
[0112] According to the condition that the intake of resveratrol reaches 1 or 2 mg per dose, weigh the required amount of resveratrol preparation, add 5 mM phosphate buffer solution (pH6.5) warmed to 37°C to make up to volume to 10 ml to prepare a test solution. Subjects (2) rinsed their mouths with distilled water and remained silent for 5 minutes. Thereafter, 10 ml of the above-mentioned test solution was contained in the mouth, and stirred with the cheeks and tongue at a speed of once / 1 second for a certain period of time without drinking. Spit out the solution...
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