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Method for increasing content of isoforskolin in coleus forskohlii fronds

A technology of Coleus forskolin flower and plant body, which is applied in the field of isofoskolin content, can solve the problems of quality impact and low content of Coleus forskolin capsules, and achieve the goal of increasing the content of Coleus forskolin without affecting the environment, The effect of simple and cheap equipment

Active Publication Date: 2014-03-26
湖北福人药业股份有限公司
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AI Technical Summary

Problems solved by technology

In order to solve the problem of medicinal material resources, Hubei University of Traditional Chinese Medicine and Hubei Furen Pharmaceutical Co., Ltd. implemented the combination of production, learning and research. Since 2001, it has been transplanted from Yunnan to Tongcheng County, Hubei Province to implement the "company + base + farmer" model for planting and construction. established a standardized planting base, and conducted pharmacognosy, quality analysis, chemical composition and pharmacology research on the medicinal materials after transplantation. The planted Coleus forskohlii plant has a low content of the main active ingredient diterpenoid isoforskolin in its medicinal materials, which has a certain impact on the quality of new varieties of Coleus forskolin Capsules.

Method used

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  • Method for increasing content of isoforskolin in coleus forskohlii fronds

Examples

Experimental program
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Effect test

Embodiment 1

[0022] 50 and 100 mg L -1 The aqueous solution of paclobutrazol should be sprayed evenly on the front and back sides of the leaves of Coleus forskohlii with fully expanded leaves in the evening, and the spraying will be stopped when the paclobutrazol solution on the leaves is about to drip. In addition, the same amount of water was taken as the above spraying amount, and the front and back sides of the leaves of Coleus forskohlii plants not sprayed with paclobutrazol solution were uniformly sprayed in the same way as a control. Spray once before pouring the seedlings, if it rains, you can re-spray. After the Coleus forskohlii plants sprayed with water and paclobutrazol solution were downed, the content of isophorskolin in Coleus forskohlii plants was detected by high performance liquid chromatography (HPLC), which was related to the amount of water sprayed. Compared with Coleus forskohlii, the results showed that the content of isophorskolin in the roots and rhizomes of Coleu...

Embodiment 2

[0024] The experiments were carried out in the same manner as in Example 1, except that concentrations of 50, 100 and 200 mg L were used -1 sprayed with salicylic acid solution. The content of isophorskolin in the roots and rhizomes of Coleus forskohlii increased by 8% to 45%, respectively.

Embodiment 3

[0026] The experiments were carried out in the same manner as in Example 1, except that concentrations of 0.2, 0.5 and 1 g L were used -1 sprayed with yeast extract solution. The content of isophoras in the roots and rhizomes of Coleus forskohlii increased by 8% to 56%, respectively.

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Abstract

The invention relates to a method for increasing content of isoforskolin in coleus forskohlii fronds, in particular to a method for increasing content of isoforskolin in coleus forskohlii fronds by an exogenous inducer.

Description

technical field [0001] The invention relates to a method for increasing the content of isforskolin in Coleus forskolin plants, in particular to a method for promoting the content of isforskolin in Coleus forskohlii plants by using an exogenous inducer Methods. Background technique [0002] Coleus forskohlii (Willd.) Briq. is a plant of the Lamiaceae Coleus genus. The curative effect is remarkable, Indian folk call it "magic medicine". In the late 1980s, Chinese botanists discovered wild Coleus forskohlii plants in Huize, Dongchuan and other places in Yunnan, and defined them as rare plant species. Modern pharmacological studies have shown that Coleus forskohlii extract has obvious pharmacological effects on bronchial asthma, congestive heart failure and various tumors. In view of the unique pharmacological effects and clinical therapeutic effects of this medicinal plant, Hubei Furen Pharmaceutical Co., Ltd. used it as the king drug, and formulated the formula with Qianhu ...

Claims

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Application Information

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IPC IPC(8): A01G7/06A01N43/653A01N37/40A01N63/04A01P21/00
Inventor 余坤刘焱文叶晓川吴宇星吴相梧王龙飞
Owner 湖北福人药业股份有限公司
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