Unlock instant, AI-driven research and patent intelligence for your innovation.

Calcium-phosphorus ceramic activated surface and preparation method thereof

A technology of calcium phosphate ceramics and calcium phosphate ceramics, which is applied in the field of ion spraying structure of calcium phosphate ceramics to activate the surface and treatment, can solve the problems of insufficient stability, high crystallinity of calcium phosphate ceramics, and reduced biological activity, and achieve a reasonable degree of crystallinity. and stability, good biological activity and biocompatibility, and the effect of improving binding strength

Active Publication Date: 2016-04-13
SOUTH CHINA UNIV OF TECH
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention aims at the problems of excessively high crystallinity of calcium phosphate ceramics, decreased biological activity and insufficient stability after surface modification caused by defects in the existing preparation process conditions, and provides a plasma sprayed calcium-phosphorus ceramic activated surface and a treatment method, Can not only construct a highly bioactive surface on the surface of calcium phosphate ceramics, but also ensure that the surface has optimized crystallinity and stability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Calcium-phosphorus ceramic activated surface and preparation method thereof
  • Calcium-phosphorus ceramic activated surface and preparation method thereof
  • Calcium-phosphorus ceramic activated surface and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Step 1: Preparation of calcium phosphorus ceramics. The calcium phosphate ceramic powder is put into the mold, and it is formed by cold isostatic pressing in an oil medium with a pressure of 175MPa. After maintaining the load for 10 hours, the ceramic body is taken out, and then the primary body is sintered at high temperature, and graphite is used as an auxiliary material. Carry out landfill sintering, the sintering temperature is 1150°C, the heating rate is 8°C / min, the heat preservation is 10h, and the sample is cooled with the furnace. The obtained bioceramics were cut into 2mm thin slices on a diamond slicer, and both sides of the thin slices were smoothed on an oil stone. Sonicate with deionized water for 5 min, rinse with deionized water for 3 times, and dry.

[0034] Step 2: Plasma spraying. Fix the ceramic sheet obtained in step (1) on the plasma sprayed sample holder, first preheat the sample at 250°C, and then use plasma spraying equipment to prepare biphas...

Embodiment 2

[0039] The calcium phosphate ceramics after plasma spraying were hydrothermally treated for 60 minutes. Other preparation and process conditions were the same as in Example 1. Needle-shaped crystals were also obtained, and the crystal size increased, with an average diameter of 20-50 nanometers and an average length of 2500 nanometers. However, a small number of needle-like crystals combined to form flaky crystals appeared.

Embodiment 3

[0041] The calcium phosphate ceramics after plasma spraying were hydrothermally treated for 90 minutes. Other preparation and process conditions were the same as in Example 1. Needle-shaped crystals were also obtained, and the crystal size varied, with an average diameter of 50-100 nanometers and an average length of 3000 nanometers. The number of flaky crystals increased significantly, and the size increased. Example 4

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
thicknessaaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a calcium phosphate ceramic activated surface and a preparation method thereof. The preparation method comprises the steps of filling calcium phosphate ceramic powder in a mould, pressing and forming by using cold isostatic pressure in an oil medium, and then sintering a primary blank at a high temperature, cutting the obtained ceramic into slices, polishing, washing and drying; and then establishing an amorphous phase bipolar calcium phosphate (BCP) surface on the surface of the ceramic by using a plasma spraying method, and converting the amorphous phase surface into an activated surface with a reasonable degree of crystallinity through a hydro-thermal treatment process. The preparation method is simple in process, high in production efficiency and good in repeatability; the calcium phosphate ceramic surface which is subjected to hydro-thermal treatment is uniform in structure, good in biological activity, excellent in biocompatibility and good in market application prospect and commercial value.

Description

technical field [0001] The invention belongs to the field of surface modification of bioceramic materials, and in particular relates to an activated surface of calcium-phosphorus ceramics with plasma spraying structure and a treatment method. Background technique [0002] HA is a ceramic material with good biocompatibility, which can form a chemical bond with the tissue at the interface after implanted in the body, and there is no connective tissue interface layer between it and the tissue, and is widely used in bone repair. But HA is too stable in the body, and its crystal structure is similar to that of bone, so it forms a chemical and biological balance with bone. While β-TCP has good osteoinductive ability, but it degrades too fast in vivo. Combining HA and β-TCP can play their respective advantages, and the comprehensive physiological properties of composite materials will be better than single-phase bioceramics. The dual-phase ceramic powder composed of hydroxyapatit...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C04B41/87
Inventor 邓春林邱萱吴刚王迎军
Owner SOUTH CHINA UNIV OF TECH