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Simultaneous non-contrast MR angiography and intraplaque hemorrhage (SNAP) MR imaging

A plaque and imaging technology, applied in the direction of using nuclear magnetic resonance imaging system for measurement, using magnetic variable measurement, instruments, etc., can solve problems such as registration difficulties, achieve effective lumen delineation, automatic matching and registration, and reduce scanning the effect of time

Active Publication Date: 2017-07-28
KONINKLJIJKE PHILIPS NV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Additionally, IPH imaging techniques generally have limited sensitivity to other aspects of the anatomy (e.g., vessel lumens), which makes localization (i.e., registration) of IPH data relative to MRA data difficult

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  • Simultaneous non-contrast MR angiography and intraplaque hemorrhage (SNAP) MR imaging
  • Simultaneous non-contrast MR angiography and intraplaque hemorrhage (SNAP) MR imaging
  • Simultaneous non-contrast MR angiography and intraplaque hemorrhage (SNAP) MR imaging

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Embodiment Construction

[0023] It is recognized herein that a technique capable of providing both magnetic resonance angiography (MRA) data and intraplaque hemorrhage (IPH) data simultaneously in one MR scan would be advantageous. Utilizing this technique not only reduces the extra scan time for IPH, but also automatically achieves spatial registration of IPH images with MRA images, thereby eliminating the need to match the two images at the time of diagnosis.

[0024] Disclosed herein are techniques that simultaneously provide both MRA data and IPH data in one MR scan. The disclosed technique is referred to herein as the simultaneous non-contrast angiography and plaque hemorrhage (SNAP) technique. SNAP offers the following advantages: (1) simultaneous detection and quantification of both luminal stenosis (via MRA) and IPH; (2) reduced scan time and improved review process by eliminating additional IPH scans, and automatic matching and registration; (3) provides both MRA and IPH data without the adm...

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Abstract

Magnetic resonance (MR) spins are inverted by applying an inversion recovery (IR) radio frequency pulse (50). MR signals are acquired at an inversion time (TI) after the IR radio frequency pulse. TI is selected such that a first tissue of interest (e.g., blood) exhibits negative magnetism excited by the IR radio frequency pulse and a second tissue (e.g., intraplaque hemorrhage tissue) exhibits positive magnetism excited by the IR radio frequency pulse. The acquired magnetic resonance signals are reconstructed to generate spatial pixels or voxels wherein positive pixel or voxel values indicate spatial locations of positive magnetism and negative pixel or voxel values indicates spatial locations of negative magnetism. A first image (28) representative of the first tissue is generated from spatial pixels or voxels having negative signal intensities, and a second image (26) representative of the second tissue is generated from spatial pixels or voxels having positive signal intensities.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Application No. 60 / 477840, filed April 21, 2011, entitled "Simultaneous Non-contrast Angiography and IntraPlaque hemorrhage (SNAP) imaging." technical field [0003] The following relates to the field of magnetic resonance, the field of magnetic resonance imaging (MRI), the field of magnetic resonance angiography (MRA), and applications involving these fields, such as medical imaging, veterinary imaging, etc. Background technique [0004] Since intraplaque hemorrhage (IPH) has been found to be associated with significantly increased clinical symptoms (stroke and / or heart disease) and accelerated disease progression, detection of IPH using MRI has clinical value. Assessment of IPH has also been found to be helpful in treatment planning, as subjects with carotid IPH have been found to be more likely to develop IPH if stenting is used for treatment compared to conventi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01R33/56
CPCG01R33/5602G01R33/5635
Inventor J·王M·G·赫勒W·S·克尔温P·博尔纳特C·袁
Owner KONINKLJIJKE PHILIPS NV