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Oral medicine for treating chronic nasosinusitis

A technology for chronic sinusitis and drugs, applied in the field of traditional Chinese medicine, can solve the problems of antibiotic side effects and drug resistance that cannot be ignored, and achieve the effects of no drug resistance, no toxic side effects, and stable curative effect.

Inactive Publication Date: 2014-06-04
NINGBO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although antibiotics are the drug of choice in the drug treatment of chronic sinusitis, their drug resistance cannot be ignored. In addition, antibiotics still have relatively large toxic and side effects

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0058] The present invention also provides a preparation method of the above-mentioned Chinese medicine for oral administration, when the dosage form of the Chinese medicine for oral administration is an oral liquid, specifically:

[0059] In the first step, the components of the above-mentioned raw materials are sent to the blender according to the stated mass and mixed in proportion, and then sent to the stainless steel extraction kettle, adding 5kg to 8kg of water, decocting for 3 to 5 hours, and filtering the decoction , add 3kg to 5kg of water to the filter residue again, decoct for 2 to 4 hours, filter the decoction, add 2kg to 3kg of water to the filter residue, decoct for 1 to 3 hours, filter the decoction, and The filtrate obtained by filtering three times is mixed to obtain an extract;

[0060] In the second step, take 0.03-0.06 times the sucrose relative to the sum of the mass of raw materials, add water to dissolve, then add to the extract obtained in the first ste...

Embodiment 1

[0064] Embodiment 1 Chinese medicine oral liquid 1

[0065]Angelica dahurica 25g, cocklebur 33g, mulberry leaves 27g, Huoxiang 19g, atractylodes 32g, asarum 53g, licorice 25g, nepeta 21g, jujube 32g, perilla leaves 27g, pangolin 26g, plantain 30g, chuanxiong 25g , Scutellaria baicalensis 41g, gardenia 28g, ebony plum 30g, aster 18g, sinensis 25g, heterophylla 41g, sealwort 35g, spiced herbs 27g and styrax 18g were mixed in a mixer, then sent into a stainless steel extraction kettle, and 7kg of water was added. Decoct for 5 hours, filter the decoction, add 4kg of water to the filter residue, decoct for 4 hours, filter the decoction, add 3kg of water to the filter residue, decoct for 2 hours, and filter the decoction , mix the filtrates obtained by three times of filtration to obtain an extract, take 30g of sucrose, dissolve it in water, then add it to the extract obtained above, concentrate, remove part of the water, and obtain a solution with a crude drug concentration of 2g / m...

Embodiment 2

[0066] Embodiment 2 Chinese medicine oral liquid 2

[0067] Angelica dahurica 23g, cocklebur 31g, mulberry leaves 25g, Huoxiang 17g, atractylodes 30g, asarum 51g, licorice 23g, nepeta 19g, jujube 30g, perilla leaves 25g, pangolin 24g, plantain 28g, chuanxiong 23g , Scutellaria baicalensis 39g, gardenia 26g, black plum 28g, aster 16g, sinensis 23g, heterophylla 39g, sealwort 33g, spiced herbs 25g and styrax 16g were mixed in a mixer, then sent into a stainless steel extraction kettle, and 7kg of water was added. Decoct for 5 hours, filter the decoction, add 4kg of water to the filter residue, decoct for 4 hours, filter the decoction, add 3kg of water to the filter residue, decoct for 2 hours, and filter the decoction , mix the filtrates obtained by three times of filtration to obtain an extract, take 30g of sucrose, dissolve it in water, then add it to the extract obtained above, concentrate, remove part of the water, and obtain a solution with a crude drug concentration of 2g / ...

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PUM

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Abstract

The invention provides an oral traditional Chinese medicine for treating chronic nasosinusitis. The oral traditional Chinese medicine is prepared from the following raw materials: radix angelicae, cocklebur fruit, folium mori, agastache rugosus, rhizoma atractylodis, asarum, licorice root, schizonepeta, fructus ziziphi jujubae, folia perillae acutae, manis pentadactyla, plantain herb, ligusticum wallichii, scutellaria baicalensis, fructus gardeniae, smoked plum, aster, carpet bugle, radix pseudostellariae, rhizoma polygonati, cortex acanthopanacis and storax. Compared with a Western medicine, the oral traditional Chinese medicine is stable in efficacy, and cannot generate medicine resistance and toxic and side effects, thereby being worthy of popularization.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an oral medicine for treating chronic sinusitis. Background technique [0002] Chronic sinusitis is a common and frequently-occurring disease in otolaryngology. It is the result of multiple factors. The core changes in its pathophysiology are the narrowing and obstruction of the sinus ostia caused by various reasons and the dysfunction of mucociliary clearance. For the treatment of chronic sinusitis, drug therapy should be the first choice, and surgical treatment should be considered only when standard drug therapy is ineffective or complications occur. The drug treatment of chronic sinusitis mainly includes anti-inflammation, anti-allergy, promoting mucociliary transmission, changing the body's immune deficiency and traditional Chinese medicine treatment. [0003] Infection is the leading cause of chronic sinusitis, and antibiotics have always been the drug...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P11/02A61K35/36
Inventor 翁婉丹江峰靳一鸣徐雷张杰古洪亮
Owner NINGBO UNIV
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