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Preparation method of nasal linalool-borneol preparation capable of calming, assisting sleeping and relieving palpitation

A technology for preparation and nasal use, which is applied in the field of preparation of aromatic ice nasal preparations, which can solve the problems of poor therapeutic effect, low bioavailability, and low patient compliance

Inactive Publication Date: 2014-07-30
FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the diversity and long-term nature of drugs for the treatment of palpitations and insomnia clinically, the frequency and inconvenience of taking drugs lead to low patient compliance, poor therapeutic effect, and the main way of administration is oral, with low bioavailability

Method used

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  • Preparation method of nasal linalool-borneol preparation capable of calming, assisting sleeping and relieving palpitation
  • Preparation method of nasal linalool-borneol preparation capable of calming, assisting sleeping and relieving palpitation

Examples

Experimental program
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Effect test

Embodiment 1

[0016] Borneol 300 g Linalool 800 ml Menthol 140g Add 90% medicinal alcohol to 1000ml

[0017] Take 300g of borneol and 140g of menthol and grind finely to form a eutectic liquid, add 150ml of 90% medicinal alcohol to dissolve, then add 800ml of liquid linalool, stir, mix well, add 90% medicinal alcohol to 1000ml, mix well to get a light yellow, transparent aromatic liquid, fill it into 100 spray bottles (10ml per bottle), and get ready.

[0018] Description of the drawings: The attached drawings are pictorial models for illustration.

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Abstract

The invention provides a preparation method of a nasal linalool-borneol preparation with main functions of calming, assisting sleeping and relieving palpitation. The nasal preparation is prepared by adding 90% medical alcohol and linalool into an oily liquid formed by virtue of eutectic performance after menthol and borneol are mixed. The nasal preparation has two administration ways of snorting and nasal spraying and is characterized in that when a patient bursts palpitation and chest distress, the liquid medicine can be directly sprayed into the nasal cavity in a nasal spray manner, and the medicament is absorbed by the nasal mucosa and the lung and enters blood circulation, so that the drug effect is quickly played to achieve the effect of quickly relieving the symptom; when a patient is insomnic, a proper amount of liquid in a bottle can be sprayed to fitting sliced cotton, and the cotton is adhered to the position of philtrum under the nose, the volatile medicament is inhaled into the lung in a gas manner while the patient is refreshing spirit by closing eyes, and the effect of calming and assisting sleeping can be achieved. The nasal linalool-borneol preparation is convenient to use, can be carried along, is aromatic in smell and small in irritation, can be well applied to various groups with insomnia and palpitation, and is especially suitable for patients with palpitation and insomnia.

Description

technical field [0001] The patent belongs to the field of traditional Chinese medicine preparations and is used for treating heart palpitations and insomnia, and relates to the preparation of a fragrant ice nose preparation that can calm sleep and relieve heart palpitations. Background technique [0002] Traditional Chinese medicine believes that palpitations include palpitations and palpitations. The name of palpitations first appeared in the book of Zhongjing. Then cause the patient's paroxysmal conscious heart to beat sharply, be alarmed and restless, and can't be autonomous as a common syndrome of the main clinical manifestations. Clinically, it often occurs due to emotional fluctuations or overwork, and is often accompanied by shortness of breath, chest tightness, insomnia, forgetfulness, and even dizziness, shortness of breath, and tinnitus. [0003] Complications of palpitations - insomnia is the most common sleep disorder, which belongs to the category of insomnia a...

Claims

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Application Information

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IPC IPC(8): A61K31/045A61K9/00A61P25/20A61P9/06
Inventor 李孝栋
Owner FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE