A kind of traditional Chinese medicine composition and application thereof for the treatment of IGA nephropathy

Abstract

The invention relates to a traditional Chinese medicine composition for treating IgA nephropathy and an application thereof. The traditional Chinese medicine composition is prepared from the following medicinal raw materials in parts by weight: 6-12 parts of radix bupleuri, 9-15 parts of scutellaria baicalensis, 6-9 parts of codonopsis pilosula, 9-15 parts of astragalus membranaceus, 15-30 parts of sculellaria barbata, 15-30 parts of oldenlandia diffusa and 15-30 parts of solanum lyratum. The traditional Chinese medicine composition has the advantages that the compatibility of the medicines is precise and appropriate, the sculellaria barbata, the oldenlandia diffusa and the solanum lyratum are monarch medicines and are capable of clearing away heat and toxic materials, dissipating stasis and dispelling dampness, the radix bupleuri is an adjuvant and can eliminate the evils located at Shaoyang yang channel, the scutellaria baicalensis can clear away the heat located at Shaoyang channel, the codonopsis pilosula and the scutellaria baicalensis are capable of benefiting qi and strengthening the body resistance so as to eliminate pathogens, and the traditional Chinese medicine composition can be used for effectively reducing the 24 hour urine protein quantitation of patients with the IgA nephropathy and improving hematuresis conditions, is low in medicine cost and has no toxic or side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating IgA nephropathy and its application, in particular to a Chinese patent medicine prepared from Chinese herbal medicines. Background technique [0002] IgA nephropathy is a group of diseases without systemic diseases. Immunopathological examination of renal biopsy shows IgA-based granular deposits in the mesangial region of the glomerulus, accompanied by mesangial cell proliferation and matrix hyperplasia. Clinically, hematuria, Proteinuria is the main manifestation of glomerulonephritis. This disease is a common clinical chronic progressive primary glomerular disease, accounting for about 38% to 42% of primary glomerulonephritis, and about 20% to 30% of patients develop end-stage renal disease. The exact pathogenesis of IgA nephropathy is not yet fully understood, and most scholars believe that it is related to various factors such as genetics, environment, infection, and ...

AI Technical Summary

Problems solved by technology

Although angiotensin-converting enzyme inhibitors (ACEI) have been proven to reduce glomerular pressure, delay renal function deterioration, reduce urinary protein (20% to 40%), and reduce glomerular sclerosis and interstitial fibrosis, But its efficacy has not yet reached the goal that doctors expect

Images