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Dracontomelon duperreanum leaf extract suspension, as well as preparation method and application thereof

A technology of leaf extract and human face cotyledon, which is applied in the field of human face cotyledon extract suspension and preparation, can solve the problems of bedsore clinical care, bed sores are easy to cause infection, sepsis death and other problems, to shorten the time of wound healing, Effective in preventing bacterial infection and definite curative effect

Inactive Publication Date: 2014-12-03
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Bed sores are easy to cause infection, and once they get worse, they will bring great pain to the patient, and even cause sepsis and death
Most decubitus ulcers are a clinical care challenge due to lack of fast-acting and effective drugs

Method used

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  • Dracontomelon duperreanum leaf extract suspension, as well as preparation method and application thereof
  • Dracontomelon duperreanum leaf extract suspension, as well as preparation method and application thereof
  • Dracontomelon duperreanum leaf extract suspension, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1: The preparation of human face cotyledon extract (50% ethanol extract):

[0031] Precisely weigh 300g of human face cotyledons, crush them, pass through a 24-mesh sieve, add 10 times the amount of 50% ethanol, extract 3 times, each time for 1.5h, combine the extracts, filter under reduced pressure, and vacuum at 50°C to 70°C The ethanol is recovered to obtain the extract of the cotyledon of human face.

Embodiment 2

[0032] Example 2: The preparation of human face cotyledon extract (60% ethanol extract):

[0033] Precisely weigh 300g of the cotyledon of human face, pulverize, pass through a 24-mesh sieve, add 10 times the amount of 60% ethanol, extract 3 times, each time for 1.5h, combine the extracts, filter under reduced pressure, and vacuum at 50°C to 70°C The ethanol is recovered to obtain the extract of the cotyledon of human face.

Embodiment 3

[0034] Example 3: The preparation of human face cotyledon extract (70% ethanol extract):

[0035] Precisely weigh 300g of cotyledons of human face, crush them, pass through a 24-mesh sieve, add 10 times the amount of 70% ethanol, extract 3 times, each time for 1.5h, combine the extracts, filter under reduced pressure, and vacuum at 50°C to 70°C The ethanol is recovered to obtain the extract of the cotyledon of human face.

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Abstract

The invention provides a dracotomelon duperreanum leaf extract suspension, as well as a preparation method and application thereof, belonging to the technical field of traditional Chinese medicine. The preparation method comprises the following steps: extracting crushed medicinal material dracotomelon duperreanum leaf for three times by 50-70% ethanol, performing suction filtration on the extract at reduced pressure, and reclaiming the ethanol in vacuum at reduced pressure to obtain a dracotomelon duperreanum leaf extract; drying the dracotomelon duperreanum leaf extract in vacuum to obtain a dry extract; preparing an aqueous solution from the dry extract, and suspending the dracotomelon duperreanum leaf extract and chitosan in honey which is used as a solvent type carrier to prepare the suspension. The invention further discloses the application of the dracotomelon duperreanum leaf extract suspension in preparing medicines for treating bedsore. The dracotomelon duperreanum leaf extract suspension has the advantages of remarkably shortening the wound healing time and effectively preventing bacterial infection caused by bedsore, and is convenient to use and exact in curative effect. By means of the preparation method, a traditional medicine is developed into a modern preparation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a human face cotyledon extract suspension, a preparation method and an application. Background technique [0002] Bed sores are capillary blockage and local ischemia caused by long-term pressure and tissue contraction. Insufficient blood perfusion and accumulation of local toxic metabolites increase the probability of cell death, which leads to ulcers in the skin and its subcutaneous tissue. Complications of clinical care that are completely avoided. According to incomplete statistics, the incidence of bedsores in hospitalized patients ranges from 5.1% to 32.1%. Predisposing factors for decubitus ulcers include age, active or passive bed rest, paralysis, forced positioning, sensory impairment, and diabetes. [0003] Bed sores are easy to cause infection, and once they get worse, they will bring great pain to the patient, and even cause sepsis an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/22A61K9/10A61P17/02
Inventor 赵艳玲肖小河王伽伯刘书显陈哲郑全福
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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