The invention discloses a medicine for treating spleen-lung qi deficiency infantile enuresis. The medicine comprises white fungus, companumoea roots, the herb of wilson passionflower, American ginseng, coix seeds, the herb of wight parnassia, water chestnut, reeves shad, roots of caragana sinica, dracontomelon duperreanum, fructus aurantii, camphor roots, shepherd's purse, hairyvein agrimony, stephania sinica diels, mentha haplocalyx, rhizoma cibotii, begonia wilsonii, agaric, codonopsis convolvulacea, bloody clam, Korean pine seeds, sugarcane, pork liver, the roots of franchet peashrub flowers, mandarin fish, arrhenatherum elatius, themeda triandra fruits and acanthopanax. The medicine has the effects of reinforcing lung to replenish qi, invigorating spleen and stomach, benefiting qi, nourishing blood and stably securing the exterior, is mainly used for treating spleen-lung qi deficiency infantile enuresis in an internal and external application mode, achieves curing and healing at the same time, is made of pure natural traditional Chinese medicinal materials, attaches great importance to the overall concept, is high in targeting property and effective in treatment, has few adverse effects, can improve overall immunity, control disease in time and reduce complications, and the like.