A plaster for treating scapulohumeral periarthritis, cervical spondylosis and rheumatoid arthritis is composed of the following components: 70g of schefflera arboricola, 55g of erberry, 70g of coralbean bark, 25g of pyrolusite, 55g of red ixora leaf, 65g of radix toddaliae asiaticae, 25g of shinyleaf pricklyash root, 55g of caryopteris incana, 55g of Chinese ivy stem, 65g of pangolin, 55g of evodia rutaecarpa, 55g of greyblue spicebush, 18g of red orpiment, 65g of rhubarb, 55g of centipede, 65g of buthus martensi karsch, 75g of buckhorn, 75g of sea horse, 75g of little multibanded krait, 65g of angelica sinensis, 65g of drynaria, 35g of rhizoma kaempferiae, 35g of clove, 35g of cinnamon, 55g of rhizome acori tatarinowii, 70g of piper wallichii, 55g of caulis trachelospermi, 65g of clematis chinensis, 55g of climbing entada stem, 55g of barren wort, 65g of sweetgum fruit, 5800g of sesame oil, 2080g of yellow lead, 55g of azone and 45g of propylene glycol. The manufacturing method of the invention comprises the following steps: 1. after weighting the crude drugs except for sesame oil, yellow lead, zone and propylene glycol, baking with a low temperature, grinding to fine powder, sieving with a No.7 sieve, preserving for standby, namely obtaining the medicine powder, and 2. decocting 5800g of sesame oil with an iron pan under slow fire to boiled, uniformly scattering 2800g of yellow lead into the sesame oil gradually, simultaneously quickly mixing with a willow roller along a same direction continuously to uniform, decocting the mixture to a state when a few amount of mixture does not disperse when dripped into the cold water and extinguishing the fire, after cooling to 60-70 DEG C, adding the medicine powder, 55g of azone and 45g of propylene glycol into the mixture, after mixing to uniform, coating on the prepared non-woven cloth or animal skin when the medicine is hot, and namely the plaster for treating rheumatism ostealgia is obtained.