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A kind of pharmaceutical composition for treating nephrotic syndrome

A technology of nephrotic syndrome and composition, applied in the directions of drug combination, pharmaceutical formula, urinary system diseases, etc., can solve problems such as no reports.

Inactive Publication Date: 2016-08-24
于晨
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report on the effect of paeonol in treating nephrotic syndrome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Weigh: 150 mg of glycyrrhizin, 60 mg of paeonol, 100 mg of puerarin, 120 mg of osthole, mix them evenly, put them into the capsule shell, and then a capsule suitable for a normal adult’s daily dose can be prepared. For the treatment of nephrotic syndrome.

[0017] The present invention is specifically described below in conjunction with clinical experiments:

[0018] 1. Objects and methods

[0019] The inventor collected a total of 40 patients from February 2010 to December 2013. The compliance of the patients was good and they could be followed up for reexamination. Among them, there were 21 males and 19 females; the age ranged from 23 to 70 years, with an average age of 46.3 years. Randomly divided into two groups: control group and observation group, 20 cases in each group, there was no statistically significant difference in gender, age, disease severity, complications, complications, etc. between the two groups (P>0.05), comparable.

[0020] 1.1 Criteria for in...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating nephrotic syndrome, which is composed of raw materials in the following weight proportions: 150 parts of glycyrrhizin, 60 parts of paeonol, 100 parts of puerarin and 120 parts of osthole. The inventors found that the composition of the present invention has obvious therapeutic effect on nephrotic syndrome.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating nephrotic syndrome. Background technique [0002] Nephrotic syndrome (NS) refers to the increased permeability of the glomerular basement membrane caused by various reasons, resulting in a large amount of protein loss, resulting in hypoalbuminemia, high edema and hypercholesterolemia. syndrome. [0003] Western medicine has not fully elucidated the pathological mechanism of nephrotic syndrome. It is generally understood that a large amount of proteinuria is caused by one or both destruction of the capillary wall charge barrier and the sieve barrier (basement membrane) of the glomerulus. The filtration function of the glomerulus is destroyed, and a large amount of plasma protein is leaked into the urine and lost, showing a series of symptoms of kidney disease. [0004] Nephrotic syndrome is characterized by "three highs and one low" (massive proteinuria, hypoproteinemia, hyperlipidemi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61P13/12A61K31/12A61K31/352
Inventor 于晨齐栋范华英
Owner 于晨