Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Monomer fragrance mal-leu for tobacco, preparation method and application thereof

A technology of monomers and spices, which is applied in the fields of flavors, flavors, and tobacco processing. It can solve the problems of maintaining the moisture content of shredded tobacco and improving the sensory comfort, etc., so as to improve the roundness and comfort of the smoke, increase the yield, and The effect of high yield

Active Publication Date: 2016-08-24
CHINA TOBACCO HENAN IND
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to improve the moisture content of shredded tobacco during processing and the processing resistance of shredded tobacco. The maintenance of moisture content and the improvement of sensory comfort are not ideal

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Monomer fragrance mal-leu for tobacco, preparation method and application thereof
  • Monomer fragrance mal-leu for tobacco, preparation method and application thereof
  • Monomer fragrance mal-leu for tobacco, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0027] Add 1 gram of maltose, 1.5 mL of dimethylformamide, and 3.0 mL of anhydrous methanol into a three-neck flask equipped with a thermometer and a condenser tube, reflux at 75°C for 23 minutes, then add 0.146 grams of leucine and reflux for another 23 minutes, and finally Add 0.033 gram of strongly acidic ion-exchange resin and 0.339 gram of myricetin for reflux reaction for 1.5h; after the reaction ends, 0.366 gram of the white crystalline target product is obtained through silica gel column chromatography separation and recrystallization; wherein, the eluent used for column chromatography separation is A mixture of n-butanol, glacial acetic acid and water, the volume ratio of the three is 5:2:1, the color developer is ninhydrin ethanol solution; the solvent used for recrystallization is absolute ethanol with a volume ratio of 1:1 mixed solution with anhydrous methanol.

Embodiment 2

[0029] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0030] Add 1 gram of maltose, 3.4 mL of dimethylformamide, and 2.1 mL of anhydrous methanol into a three-necked flask equipped with a thermometer and a condenser, and reflux at 82°C for 29 minutes, then add 0.268 grams of leucine and reflux for another 29 minutes, and finally 0.055 g of strong acidic ion exchange resin and 1.016 g of myricetin were added for reflux reaction for 3.5 h; after the reaction, 0.819 g of the target product Mal-Leu in the form of white crystals was obtained through silica gel column chromatography and recrystallization. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

Embodiment 3

[0032] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0033] Add 1 gram of maltose, 3.8 mL of propylene glycol and 1.6 mL of anhydrous methanol into a three-necked flask with a thermometer and a condenser tube, reflux at 89°C for 43 minutes, then add 0.364 grams of leucine and reflux for another 43 minutes, and finally add 0.065 grams of strong The acidic ion exchange resin and 1.694 g of myricetin were refluxed for 7.5 hours; after the reaction, 0.605 g of the target product in the form of white crystals was obtained through silica gel column chromatography and recrystallization. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

[0034] (1) Structural characterization of the target product

[0035] Through infrared spectroscopy (IR), high-resolution mass spectrometry (HR-MS), carbon nuclear magnetic resonance spectroscopy ( 13 C-NMR) carry out structural character...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention belongs to the field of flavors and fragrances and tobacco processing, and in particular relates to a novel monomer fragrance Mal-Leu for cigarettes, a preparation method and an application. The structural formula of the monomer fragrance Mal-Leu for tobacco is as follows:. The present invention tests the physical moisture retention performance of cigarettes and evaluates the internal sensory quality of finished cigarettes, and finds that it can not only significantly improve the physical moisture retention performance of shredded tobacco, but also significantly improve the sensory quality of cigarettes and reduce the irritation of cigarettes. Sex and miscellaneous gas, enhance the roundness of cigarette smoke.

Description

technical field [0001] The invention belongs to the field of flavors and fragrances and tobacco processing, and in particular relates to a novel monomer fragrance Mal-Leu for cigarettes, a preparation method and an application. Background technique [0002] As people pay more and more attention to smoking and health problems, while further reducing the amount of tar in cigarettes, the comfort of cigarettes becomes worse, which is mainly reflected in the loss of water dispersion in shredded tobacco, low moisture in mainstream smoke, high irritation, and dry mouth And phlegm etc. At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to improve the moisture content of shredded tobacco during processing and the processing resistance of shredded tobacco. The maintenance of moisture content and the improvement of sensory comfort are not ideal. Contents of the invention [0003] Th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07H3/08C07H1/00A24B15/40
Inventor 芦昶彤陈芝飞郝辉李怀奇孙志涛马宇平
Owner CHINA TOBACCO HENAN IND
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com