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A traditional Chinese medicine extract product for treating chloasma and its preparation method

An extract and technology for chloasma, applied in the field of medicine, can solve the problems of undiscovered winter mulberry leaf extract, less research on treatment or health care, etc., and achieve the effect of remarkable drug effect, high utilization, and elimination of pigmentation

Active Publication Date: 2017-03-29
GUIZHOU SHENQI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many studies on the above-mentioned mulberry leaf and peony seed oil for freckle removal, but there are few studies on the treatment or health care of specific diseases using the active ingredient extracts of medicinal materials. Research report on removing chloasma

Method used

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  • A traditional Chinese medicine extract product for treating chloasma and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1: extract preparation

[0077] 1) Winter mulberry leaf extract: Take winter mulberry leaves, remove impurities, add 8 times the amount of water to reflux and extract twice, each time for 2 hours, filter, combine the filtrates, concentrate under reduced pressure to form a thick paste, then add 4 times the amount of 75% Ethanol, fully stirred evenly, left standing for 24 hours, filtered, the filtrate was decompressed to recover ethanol, and concentrated into a thick paste with a relative density of 1.20 at 60°C, to obtain the winter mulberry leaf extract;

[0078] 2) Peony seed oil: peeled and dried peony seeds, crushed into 80 meshes, added petroleum ether with a boiling range of 60-90°C, the liquid-to-solid ratio of the petroleum ether and peony seeds was 9ml / g, and mixed well Then put it into an ultrasonic processor, adjust the power to 250W, and the temperature is 50°C. After ultrasonic treatment for 30 minutes, separate the solvent mixture and residue, re...

Embodiment 2

[0079] Embodiment 2: extract preparation

[0080] 1) Winter mulberry leaf extract: Take winter mulberry leaves, remove impurities, add 6 times the amount of water to reflux and extract 3 times, each time for 1 hour, filter, combine the filtrates, concentrate under reduced pressure to form a thick paste, then add 5 times the amount of 60% Ethanol, fully stirred evenly, allowed to stand for 18 hours, filtered, and the filtrate was decompressed to recover ethanol, and concentrated into a thick paste with a relative density of 1.10 at 60°C to obtain the winter mulberry leaf extract;

[0081] 2) Peony seed oil: shelled and dried peony seeds, crushed into 60 meshes, added petroleum ether with a boiling range of 60-90°C, the liquid-to-solid ratio of the petroleum ether and peony seeds was 10ml / g, and mixed well Then put it into an ultrasonic processor, adjust the power to 200W, and the temperature is 60°C. After ultrasonic treatment for 20 minutes, separate the solvent mixture and re...

Embodiment 3

[0082] Embodiment 3: extract preparation

[0083] 1) Winter mulberry leaf extract: Take winter mulberry leaves, remove impurities, add 10 times the amount of water to reflux for extraction for 3 hours, filter, combine the filtrate, concentrate under reduced pressure to form a thick paste, then add 3 times the amount of 85% ethanol, and stir well , stand still for 12 hours, filter, the filtrate recovers ethanol under reduced pressure, and concentrates it into a thick paste with a relative density of 1.30 at 60°C, to obtain the winter mulberry leaf extract;

[0084] 2) Peony seed oil: shelled and dried peony seeds, crushed into 100 meshes, added petroleum ether with a boiling range of 60-90°C, the liquid-to-solid ratio of the petroleum ether and peony seeds was 5ml / g, and mixed evenly Then put it into an ultrasonic processor, adjust the power to 300W, and the temperature is 40°C. After ultrasonic treatment for 40 minutes, separate the solvent mixture and residue, recover petrole...

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Abstract

The invention discloses a traditional Chinese medicine extract product for treating chloasma and a preparation method for the traditional Chinese medicine extract product. The traditional Chinese medicine extract product is prepared from the following raw material medicines in parts by weight: 1.0-3.5 parts of a winter folium mori extract and 1.0-2.4 parts of peony seed oil. With the combination of traditional Chinese medicines and modern preparation processes, cosmetics which can be applied to skin can be prepared, the utilization rate of the traditional Chinese medicine extract is increased, the healthcare function of medicines is improved, and the traditional Chinese medicine extract product is particularly applicable to development of modernization of traditional Chinese medicines and massive health products.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract product for treating chloasma and a preparation method thereof, in particular to a method for making health care products or cosmetics by using the traditional Chinese medicine extract, belonging to the technical field of medicine. Background technique [0002] Facial pigmentation is a clinically common symptom on the outer layer of the skin. It can occur in both men and women, especially in women, especially in married women. Uncertain, hindering the appearance of the face. Mainly divided into freckles, chloasma, skin melanosis and other pigmented lesions. Chloasma is commonly known as "butterfly spots", "liver spots" or "pregnancy spots". It mainly occurs on the face, mainly in the cheeks, cheeks, nose, forehead, and chin. Brown or black patches with indistinct borders, mostly symmetrical. The appearance of chloasma is mostly related to endocrine, especially related to estrogen level...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/98A61K8/11A61Q19/00A61P17/00
Inventor 张芝庭张涛涛
Owner GUIZHOU SHENQI PHARMA RES INST
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