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Beam shaper for neutron-capture therapy

A body shaping and neutron technology, applied in the beam shaping body field of neutron capture therapy, can solve problems such as poor treatment effect and normal tissue damage

Active Publication Date: 2015-04-15
NEUBORON MEDTECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment of more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) is often less effective

Method used

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  • Beam shaper for neutron-capture therapy
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  • Beam shaper for neutron-capture therapy

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Embodiment Construction

[0024] The application of neutron capture therapy as an effective means of treating cancer has gradually increased in recent years, among which boron neutron capture therapy is the most common, and neutrons supplying boron neutron capture therapy can be supplied by nuclear reactors or accelerators. The embodiment of the present invention takes the accelerator boron neutron capture therapy as an example. The basic components of the accelerator boron neutron capture therapy generally include an accelerator for accelerating charged particles (such as protons, deuterons, etc.), targets and heat removal System and beam shaper, in which the accelerated charged particles interact with the metal target to generate neutrons, according to the required neutron yield and energy, the available accelerated charged particle energy and current, and the physical and chemical properties of the metal target To select the appropriate nuclear reaction, the nuclear reactions that are often discussed...

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Abstract

The invention provides a beam shaper for neutron-capture therapy in order to improve flux and quality of a neutron source. The beam shaper comprises a target, a slowing body adjacent to the target, a reflector wrapping the slowing body, a thermal neutron absorber adjacent to the slow body, a radiation shield arranged in the beam shaper and a beam outlet. The target generates nuclear reaction with a proton beam incident from a beam inlet so as to generate neutrons, the neutrons form a neutron beam which defines a main axis, the slowing body slows down the neutrons generated from the target to an epithermal neutron energy region, the reflector guides the neutrons deviating from the main axis to the main axis so as to improve intensity of the epithermal neutron beam, a gap passage is arranged between the slowing body and the reflector so as to improve epithermal neutron flux, the thermal neutron absorber is used for absorbing the thermal neutron so as to avoid causing overmuch dosed with shallow normal tissue during therapy, and the radiation shield is used for shielding leaked neutrons and photon so as to reduce normal tissue dose in a non-radiation region.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment outcomes for more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) are often poor. [0003] In order to reduce the radiation damage to normal tissues around the tumor, the concept of targeted therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells wit...

Claims

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Application Information

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IPC IPC(8): A61N5/10
Inventor 刘渊豪李珮仪
Owner NEUBORON MEDTECH
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