Processing method of scutellaria baicalensis

A technology of processing method and heating method, which can be applied in pharmaceutical formulations, plant raw materials, plant/algae/fungus/moss components, etc., can solve the problems of high cost, uneven quality of medicinal materials, complicated production process, etc., to eliminate the price gap. , protection of wild resources, the effect of protecting wild resources

A technology of processing method and heating method, which can be applied in pharmaceutical formulations, plant raw materials, plant/algae/fungus/moss components, etc., can solve the problems of high cost, uneven quality of medicinal materials, complicated production process, etc., to eliminate the price gap. , protection of wild resources, the effect of protecting wild resources

CN104523834AInactive Publication Date: 2015-04-22HEILONGJIANG UNIV OF CHINESE MEDICINE
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: at first the collected fresh roots of Scutellaria baicalensis are washed, then the fresh roots are treated at a constant temperature, the constant temperature temperature range is 30-60 ℃ and the fresh root is sprayed with clear water, the constant temperature temperature range is 30-65 ℃ and the The fresh roots are sprayed with clean water to keep the humidity of the fresh roots at 60-100%, and this state is maintained for 1-3 days, and the moisturizing treatment of the fresh roots is stopped.

[0022] Principle of processing method: The main component of Scutellaria baicalensis is chromone, and its key synthesis enzyme is phenylalanine ammonia lyase (PAL). The optimum temperature of this enzyme is very high, generally 30-65 °C. Among the four flavonoids with high content in Scutellaria baicalensis, baicalein has the highest bioavailability and the strongest activity. The enzymes that convert baicalin to baicalein require glucosidase, and the optimum temp...

Embodiment 2

[0024] Example 2: First, the collected fresh roots of Scutellaria baicalensis were washed, and then the fresh roots were subjected to a temperature change treatment, and the temperature change temperature range was 30-65 ° C and fresh water was sprayed on the fresh roots to keep the fresh root humidity at 60-100% , maintain this state for 1-3 days, and stop moisturizing the fresh root.

[0025] Principle of processing method: The main component of Scutellaria baicalensis is chromone, and its key synthesis enzyme is phenylalanine ammonia lyase (PAL). The optimum temperature of this enzyme is very high, generally 30-65 °C. Among the four flavonoids with high content in Scutellaria baicalensis, baicalein has the highest bioavailability and the strongest activity. The enzymes that convert baicalin to baicalein require glucosidase, and the optimum temperature of this enzyme is also very high, generally 30-65 °C. Although the roots of the newly harvested Scutellaria baicalensis lea...

Embodiment 3

[0027] Embodiment 3: at first the collected fresh roots of Scutellaria baicalensis are washed, and then the fresh roots are treated at a constant temperature and then a temperature change treatment, and the temperature change temperature range is 30-65 ° C and fresh water is sprayed on the fresh roots, and the fresh roots are covered. plastic to keep the fresh root humidity at 60-100%, maintain this state for 1-3 days, and stop moisturizing the fresh root.

[0028] Principle of processing method: The main component of Scutellaria baicalensis is chromone, and its key synthesis enzyme is phenylalanine ammonia lyase (PAL). Among the four flavonoids with high content in Scutellaria baicalensis, baicalein has the highest bioavailability and the strongest activity. The enzymes that convert baicalin to baicalein require glucosidase, and the optimum temperature of this enzyme is also very high, generally 30-65 °C. Although the roots of the newly harvested Scutellaria baicalensis leave ...

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Abstract

The invention discloses a processing method of scutellaria baicalensis, and belongs to the technical field of processing of medicinal materials. The method comprises the following steps: firstly, cleaning collected fresh roots of scutellaria baicalensis; simultaneously heating the fresh roots, and carrying out moisturizing treatment on the fresh roots; keeping the humidity of the fresh roots at 60%-100%, maintaining the state for 1-3 days, and stopping moisturizing of the fresh roots. According to the processing method, the quality of the medicinal materials is improved; the primary metabolism level of the scutellaria baicalensis is improved; the high-yield potential of the medicinal materials is fully excavated; the components are purely natural; the processing technique is designed according to the influence on the quality of the medicinal materials caused by adverse natural environment; the biosynthesis is promoted by the natural process of scutellaria baicalensis biosynthesis, and is different from a biotransformation technology; no reagent is needed to promote high expression of the secondary metabolism pathway; the components contained by the medicinal material of the scutellaria baicalensis are purely natural; and no ingredient with toxic and side effects is generated.

Description

technical field [0001] The invention belongs to the technical field of medicinal material processing, and particularly relates to a processing method of Scutellaria baicalensis. Background technique [0002] Scutellaria baicalensis is a commonly used bulk medicinal material in China. It has antipyretic, antibacterial, sedative, blood pressure, and transaminase-lowering effects. Element. Phenylalanine ammonia lyase (PAL) is a key enzyme in the biosynthesis of chromone and regulates the rate of chromone synthesis. Through the literature search on phenylalanine ammonia lyase, it is found that only yam, ginkgo biloba, Dendrobium Huoshan, cabbage type rape, chickpea and other plants have been studied at present, but the highest level of this enzyme is found in all the plants studied. The suitable temperature is very high, generally 40-60 ℃. Generally, aglycone substances are easier to absorb. Scutellaria baicalensis contains Cimicifolin and Cimicifugain, and Scutellaria baical...

Claims

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Application Information

Patent Timeline
22 Apr 2015
Publication
CN104523834A
IPC
A61K36/539
Inventors
孟祥才; 付晓莹