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Termite capsule and preparation method thereof

A technology of termites and capsules, which is applied in capsule delivery, digestive system, medical raw materials derived from arthropods, etc., can solve the problems of complicated process and single curative effect, and achieve the effect of tumor cell inhibition and improvement of hepatitis

Active Publication Date: 2015-04-29
江西中天医药生物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, termites are made into capsules and mixed with other traditional Chinese medicines. The process is more complicated and the curative effect is relatively simple.

Method used

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  • Termite capsule and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Termite capsule and preparation method thereof, the specific technological process is as follows:

[0020] (1) Mixing: dry the black-winged termites, yellow-winged termites and domestic termites with a weight ratio of 2:6:1, and mix them to obtain a dried termite product;

[0021] (2) Crush: Crush the dried termite product through 40 meshes, weigh it for later use;

[0022] (3) Heating and reflux: Add 9 times the weight of 60% ethanol to the dried termite product, heat and reflux at 60°C for 40 minutes, and cool to room temperature for later use;

[0023] (4) Enzymolysis: add the cooled solution into a multifunctional extraction tank, heat to 40°C, adjust the pH to 8, add 1% neutral lipase and 2% neutral protease of the total weight of the solution , heat preservation and enzymatic hydrolysis for 6 hours;

[0024] (5) Filtration, concentration and drying: Filter the hydrolyzed solution through a plate-and-frame filter to collect the filtrate, then centrifuge the filtr...

Embodiment 2

[0028] Termite capsule and preparation method thereof, the specific technological process is as follows:

[0029] (1) Mixing: Dry the black-winged termites, yellow-winged termites and house termites with a weight ratio of 2:7:1, and mix them to obtain a dried termite product;

[0030] (2) Crush: crush the dried termite product through 50 meshes, weigh it for later use;

[0031] (3) Heating and reflux: Add 10 times the weight of 60% ethanol to the dried termite product, heat and reflux at 70°C for 50 minutes, and cool to room temperature for later use;

[0032] (4) Enzymolysis: Add the cooled solution into a multifunctional extraction tank, heat it to 45°C, adjust the pH to 8, add 1.5% neutral lipase and 3% neutral protease by total weight of the solution , heat preservation and enzymatic hydrolysis for 8 hours;

[0033] (5) Filtration, concentration and drying: Filter the hydrolyzed solution through a plate-and-frame filter to collect the filtrate, then centrifuge the filtra...

Embodiment 3

[0037] Termite capsule and preparation method thereof, the specific technological process is as follows:

[0038] (1) Mixing: dry the black-winged termites, yellow-winged termites and domestic termites with a weight ratio of 2:8:1, and mix them to obtain a dried termite product;

[0039] (2) Crush: crush the dried termite product through 60 mesh, weigh it for later use;

[0040] (3) Heating and reflux: Add 11 times the weight of 60% ethanol to the dried termite product, heat and reflux at 80°C for 60 minutes, and cool to room temperature for later use;

[0041] (4) Enzymolysis: add the cooled solution into a multifunctional extraction tank, heat to 50°C, adjust the pH to 8, add 2% neutral lipase and 4% neutral protease by total weight of the solution , heat preservation and enzymatic hydrolysis for 10 hours;

[0042] (5) Filtration, concentration and drying: The hydrolysis solution completed by enzymolysis is filtered through a plate and frame filter to collect the filtrate,...

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Abstract

The invention discloses a termite capsule and a preparation method thereof. With termite dry powder as a main raw material, the termite capsule is refined by hydrolysis reaction of neutral fat enzyme and neutral protease and combination of heating refluxing and enzyme hydrolysis. The termite capsule is a purely natural insect type biological response modifier (BRM), has the effect of enhancing the immunity, coordinating the organism, removing different cells in a body, and forming an internal environment which is not suitable for survival of tumors, so that self-alignment of tumor cells is prompted; the proliferation, diffusion and transfer are prevented; the termite capsule is a good auxiliary therapeutic agent for hepatitis B; and the immune function of a patient with hepatitis b can be obviously improved.

Description

technical field [0001] The invention relates to termite capsules and a preparation method thereof, belonging to the field of pharmaceutical preparations. Background technique [0002] Termites (termite, white ant), also known as insects, are Arthropods, Insecta, Isoptera, similar to ants in social life, termites are distributed in tropical and subtropical regions, and feed on wood or cellulose. Termites are polymorphic, gregarious insects with strict division of labor. Once the colony organization is destroyed, it is difficult to continue to survive. [0003] Although termites endanger housing construction, reservoir dams, forest orchards, vehicles and ships, etc., they cause great losses to the national economy. But there is also an advantage. Termites have certain pharmacological effects and medicinal value, and can treat some human diseases. [0004] At present, termites are made into capsules and mixed with other traditional Chinese medicines, the process is more compl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K9/48A61P37/04A61P1/16A61P31/20
Inventor 高国文
Owner 江西中天医药生物有限公司
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