Beam shaping body for neutron capture therapy

A technology for shaping body and neutron, which is applied in the field of beam shaping body for neutron capture therapy, which can solve the problems of normal tissue damage and poor treatment effect.

Active Publication Date: 2015-04-29
NEUBORON MEDTECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path;

Method used

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  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy
  • Beam shaping body for neutron capture therapy

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Embodiment Construction

[0024] The application of neutron capture therapy as an effective means of treating cancer has gradually increased in recent years, among which boron neutron capture therapy is the most common, and neutrons supplying boron neutron capture therapy can be supplied by nuclear reactors or accelerators. The embodiment of the present invention takes the accelerator boron neutron capture therapy as an example. The basic components of the accelerator boron neutron capture therapy generally include an accelerator for accelerating charged particles (such as protons, deuterons, etc.), targets and heat removal System and beam shaper, in which the accelerated charged particles interact with the metal target to generate neutrons, according to the required neutron yield and energy, the available accelerated charged particle energy and current, and the physical and chemical properties of the metal target To select the appropriate nuclear reaction, the nuclear reactions that are often discussed...

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Abstract

In order to improve the flux and the quality of a neutron source, the invention provides a beam shaping body for neutron capture therapy. The beam shaping body comprises a beam inlet, a target, a retarding body adjacent to the target, a reflecting body surrounding the external of the retarding body, a thermal neutron absorber adjacent to the retarding body, and a radiation shield and a beam outlet formed in the beam shaping body, wherein the target has nuclear reaction with proton beam entering from the beam inlet, so as to produce a neutron; the neutron forms a neutron beam; the neutron beam defines a main axis; the retarding body slows down the neutron produced by the target to an epithermal neutron energy region; the retarding body is designed to a shape containing at least one cone; the reflecting body guides the neutron deviated from the main axis back to the main axis, so as to improve the strength of an epithermal neutron beam; the thermal neutron absorber is used for absorbing a thermal neutron, so as to prevent the thermal neutron from causing excessive dosage with a superficial normal tissue during therapy; the radiation shield is used for shielding leaked neutron and photon, so as to reduce the normal tissue dosage of a non-irradiated region.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment outcomes for more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) are often poor. [0003] In order to reduce the radiation damage to normal tissues around the tumor, the concept of targeted therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells wit...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/1001A61N5/1042A61N5/1077A61N2005/109
Inventor 刘渊豪李珮仪
Owner NEUBORON MEDTECH
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