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Snake oil preparation with high stability and preparation method of snake oil preparation
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A high-stability, snake oil technology, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problem of excessive surfactant and reduce the surfactant content in nano snake oil preparations, etc. problem, to achieve the effect of high stability
Inactive Publication Date: 2015-05-20
SHENZHEN AESTHETIC BIOLOGICAL TECH +1
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Problems solved by technology
[0009] The present invention aims to solve the problem that the surfactant is too high in the product invented by the above technology, and effectively reduce the content of the surfactant in the nano snake oil preparation by adding a nonionic surfactant and by means of homogenization
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Embodiment 1
[0034] Embodiment 1: snake oil preparation
[0035] 1. Composition:
[0036]
[0037] Nonionic surfactant and snake oil mass ratio among the present embodiment, ratio is 0.7.
[0038] 2. Preparation method:
[0039] 1) Weigh phospholipids, glycerin and water according to the above prescription, and shear at a high speed under the condition of 8000rpm until there is no visible solid in the system;
[0040] 2) Add snake oil, Span 80, and polyglycerol monooleate to the product of step 1), and continue high-speed shearing at 12,000 rpm for 10 minutes to obtain colostrum;
[0041] 3) The colostrum obtained in step 2) is subjected to 10 high-pressure homogenization cycles under the condition of 800 bar to obtain a transparent and clear snake oil preparation.
Embodiment 2
[0042] Embodiment 2: snake oil preparation
[0043] 1. Composition:
[0044]
[0045] Nonionic surfactant and snake oil mass ratio among the present embodiment, ratio is 0.73.
[0046] 2. Preparation method:
[0047] 1) Weigh phospholipids, glycerin and water according to the above prescription amount, and shear at a high speed at 12000rpm until there is no visible solid in the system;
[0048] 2) Add snake oil, Span 80, and polyglycerol monooleate to the product of step 1), and continue high-speed shearing at 10,000 rpm for 10 minutes to obtain colostrum;
[0049] 3) The colostrum obtained in step 2) is processed by a high-pressure homogenizer under the condition of 1200 bar, and circulated for 5 times to obtain a transparent and clear snake oil preparation.
Embodiment 3
[0050] Embodiment 3: snake oil preparation
[0051] 1. Composition:
[0052]
[0053] Nonionic surfactant and snake oil mass ratio among the present embodiment, ratio is 0.725.
[0054] 2. Preparation method:
[0055] 1) Weigh phospholipids, glycerin and water according to the prescription amount, and shear at a high speed under the condition of 10000rpm until there is no visible solid in the system;
[0056] 2) Add snake oil, Span 80, polyglycerol monooleate, Tween 80, and polyoxyethylene castor oil to the product of step 1), and continue high-speed shearing at 12,000 rpm for 10 minutes to obtain colostrum;
[0057] 3) The colostrum obtained in step 2) is processed by a high-pressure homogenizer under a pressure of 1500 bar, and circulated for 5 times to obtain a transparent and clear snake oil preparation.
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Abstract
The invention relates to a snake oil preparation with high stability and a preparation method of the snake oil preparation. The snake oil preparation is prepared from the following components in parts by weight: 1-30 parts of snake oil, 1-20 parts of phospholipid, 0.5-10 parts of a nonionic surfactant and 65-90 parts of disperse medium. The phospholipid, the nonionic surfactant and the disperse medium are added to snake oil by the inventor and are homogenized to prepare the snake oil preparation. The snake oil preparation is repeatedly frozen and thawed, and even is stored at 37 DEG C. The product appearance provided by the invention is capable of still keeping a transparent uniform phase, is free of wall hanging or layering, and has good mobility; and a comparison product is not clear in appearance, and serious in the phenomena such as layering and wall hanging. The comparison proves that the product provided by the invention is high in stability; and the mean grain size of the emulsified product provided by the invention is smaller than 150nm, and is superior to that of the prior art.
Description
technical field [0001] The invention relates to a preparation containing snake oil, in particular to a highly stable snake oil preparation and a preparation method thereof. Background technique [0002] The fat of snakes is snake oil, which contains unsaturated fatty acids, linolenic acid, and linoleic acid, and has good permeability. Snake oil is a traditional pure natural skin care product in my country. People have used snake oil for hundreds of years to treat burns and to condition dry, wrinkled, rough skin. Because of its delicate texture, it feels cool and comfortable when used, and has excellent compatibility and complementarity with the physiological growth characteristics of human skin. It has a good penetration, moisturizing and repairing effect on the skin, and is very suitable for people to use for physical therapy and maintenance. skin. Snake oil does not have any side effects and adverse reactions to the human body. Now, in my country, Japan, Southeast Asia...
Claims
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Application Information
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