Ultrasonographic perfusion parameter imaging method based on single-pixel TIC source

Abstract

The invention provides an ultrasonographic perfusion parameter imaging method based on a single-pixel TIC source. The method comprises the following steps: extracting original TIC under each pixel unit of an ultrasonographic sequence video image; carrying out effective TIC screening, bidirectional weighted moving average filtering and bolus perfusion model fitting on the original TIC to obtain a high-SCR single-pixel TIC matrix; respectively extracting time class, strength class and specific value class of perfusion parameter matrixes in the single-pixel TIC matrix, and carrying out pseudo-color encoding. The process of extracting the TIC of the ultrasonographic sequence video image by single pixel ROI is automatically carried out, and the SCR of the TIC under the single-pixel ROI is greatly improved and the interference of noise wave is inhibited by virtue of the combination of bidirectional weighted moving average filtering and lognormal bolus perfusion model fitting. Compared with traditional perfusion parameter evaluation and imaging, the ultrasonic blood perfusion parameter imaging based on the single-pixel TIC source contains the most abundant detail information and is more visual.

Description

technical field [0001] The invention relates to the technical field of contrast-enhanced ultrasound imaging, in particular to an imaging method of ultrasound blood perfusion parameters based on a single-pixel TIC source. Background technique [0002] The development of contrast-enhanced ultrasound microbubbles and contrast-enhanced imaging methods has made it possible to quantitatively estimate blood perfusion with contrast-enhanced ultrasound. Although the spatial resolution of contrast-enhanced ultrasound imaging is limited and individual capillaries cannot be identified, the echo signal intensity caused by contrast-enhanced microbubbles is proportional to the concentration of microbubbles and also proportional to tissue blood volume. The discovery of this proportional relationship has been made in recent years To promote the development of an important application of contrast-enhanced ultrasound imaging, that is, the estimation of perfusion parameters. Contrast-enhanced ...

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Problems solved by technology

[0005] Aiming at the limitations of extraction of TIC under conventional large ROI for ultrasound-enhanced blood perfusion parameter imaging (subjective variability, difficulty in repeated implementation, lack of detail information and low detail resolution), the purpose of the present invention is to provide a method based on Contrast-enhanced Ultrasound Perfusion Parametric Imaging Method with Single-pixel TIC Source

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