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Medicinal uses of geniposide

A technology of geniposide and application, which is applied in the field of geniposide in the field of preparation of arrhythmia treatment drugs, can solve the problem of no clinical report of geniposide arrhythmia, etc., and achieves the advantages of improving drug treatment effect, definite curative effect and improving drug utilization rate. Effect

Active Publication Date: 2019-05-10
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] After searching, it is found that there is no clinical report on the treatment of arrhythmia by geniposide in the prior art

Method used

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  • Medicinal uses of geniposide
  • Medicinal uses of geniposide
  • Medicinal uses of geniposide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The present invention is further described below through specific examples, but the examples do not limit the present invention in any way. Embodiment 1 geniposide injection

[0019]

[0020] Preparation process: Mix the prescribed amount of propylene glycol and ethanol evenly, add geniposide, stir to dissolve, add the prescribed amount of 0.9% sodium chloride solution, stir evenly, add 0.5% activated carbon for needles, stir, and decarbonize to obtain the product.

Embodiment 2

[0021] Embodiment 2 geniposide injection

[0022]

[0023] Preparation process: Add geniposide to the prescribed amount of PEG-400, stir to dissolve, add 0.9% sodium chloride solution to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and obtain.

Embodiment 3

[0024] Embodiment 3 geniposide injection

[0025]

[0026] Preparation process: Mix the prescribed amount of ethanol and Tween-80 evenly, add geniposide, stir to dissolve, add water for injection to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and obtain.

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Abstract

The invention relates to a new medical application of geniposide, which belongs to the medicine field, and especially relates to an application of geniposide in preparation of medicine for treating arrhythmia. For increasing the medicine selection of the patients with arrhythmia and reducing the toxic and side effect of the chemical medicine in the treatment process, the invention provides the medicine containing the traditional Chinese medicine active components for treating arrhythmia. The medicine takes geniposide as a main active component, which can obviously delay ventricular premature beat time of a mice arrhythmia model. The medicine for treating geniposide has the advantages of definite therapeutic effect and low adverse reaction, and is hopeful to become the novel clinical treatment medicine.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a new medical use of geniposide, in particular to the use of geniposide in preparing drugs for treating arrhythmia. Background technique [0002] Arrhythmia (cardiacarrhythmia) refers to any abnormality in the origin of heart rhythm, heart rate and rhythm, and impulse conduction. The meaning of words such as "cardiac rhythm disorder" or "arrhythmia" emphasizes the abnormality of rhythm, and arrhythmia includes both rhythm and abnormal frequency, which is more accurate and appropriate. A normal heart rhythm originates from the sinoatrial node, with a frequency of 60 to 100 beats / min (adult), which is relatively regular. The sinoatrial node impulse excites the atrium and ventricle sequentially through the normal atrioventricular conduction system, and the conduction time is constant (0.12-1.21 seconds for adults); the conduction time for the impulse to reach the ventricular muscle through th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61P9/06
Inventor 赵志全李欣刘松燕刘冬光李会恩
Owner LUNAN PHARMA GROUP CORPORATION
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